Aibinu, I., Adenipekun, E. and Odugbemi, T. (2004) Emergence of Quinolone Resistance amongst Escherichia coli Strains Isolated from Clinical Infections in Some Lagos State Hospitals in Nigeria. Nigeria Journal Health Biomedical Science, 3, 73-78.
ABSTRACT: Pterocarpus osun plant has been used overtime in the indigenous system of medicine. In this study, methanol, ethanol and aqueous extracts of leaves of P. osun were examined against five Escherichia coli strains obtained from wounds. Antibacterial effect of the plant leaves, in the concentration of 100 mg/ml, was determined using disc diffusion method. Phytochemical screening of extracts of the leaves revealed the presence of phenols, flavonoids, tannins, terpenoids alkaloids, and glycosides. Leaves extracts of P. osun showed different zones of inhibition to the Escherichia coli isolates in the different solvents used. Results from this study showed that extracts of P.osun had broad spectrum of activity on the tested bacteria.