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van den Boogaard, J., Boeree, M.J., Kibiki, G.S. and Aarnoutse, R.E. (2011) The Complexity of the Adherence-Response Relationship in Tuberculosis Treatment: Why Are We Still in the Dark and How Can We Get Out? Tropical Medicine and International Health, 16, 693-698.
http://dx.doi.org/10.1111/j.1365-3156.2011.02755.x

has been cited by the following article:

  • TITLE: Factors Affecting Treatment Interruption among TB Patients in Lagos Nigeria: Is There Any Need for Treatment Supporters?

    AUTHORS: Olusola Adedeji Adejumo, Olusoji James Daniel, Andrew Folarin Otesanya, Temitope Ashipa, Esther Ngozi Adejumo, Husseine A. Abdur-Razzaq

    KEYWORDS: Treatment Supporter, Treatment Interruption, Tuberculosis, DOTS, Nigeria

    JOURNAL NAME: International Journal of Clinical Medicine, Vol.7 No.6, June 23, 2016

    ABSTRACT: Background: This study assessed treatment interruption of tuberculosis (TB) patients managed by treatment supporters and health care workers and other predictors of treatment interruption. Methods: A descriptive cross-sectional study was conducted. Four hundred and seventy new smear positive TB patients above 14 years of age were consecutively recruited between October 1 and December 31 2012 from 34 (23 public and 11 private) directly observed treatment short course (DOTS) facilities that offered TB treatment and microscopy services. They were followed up till treatment was completed. Logistic regression was used to assess the predictors of treatment interruption. Results: A significantly higher proportion of smokers (58.6% vs 38.3%, p = 0.030), patients supervised by treatment supporters (44.4% vs 34.7%, p = 0.032), patients not counselled before initiation of treatment (55.6% vs 38.2%, p = 0.041), patients managed at private DOTS facilities (50% vs 36.3%, p = 0.010) and TB/HIV co-infected patients (54.2% vs 38.6%, p = 0.038) had treatment interruption. Predictors of treatment interruption were supervision by treatment supporters, smoking, lack of pre-treatment counselling and TB/HIV co-infection. Conclusion: A higher proportion of patients supervised by treatment supporters had treatment interruption than those supervised by health care workers. There may be a need to review the concept of treatment supervision by treatment supporters in Lagos state Nigeria.