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Ezeibe, M.C.O. (2014) The Medicinal Synthetic Aluminum-Magnesium Silicate (Nanoparticles)—Antiviral Agent and Adjuvant to Chemotherapeutics. Federal Republic of Nigeria Patents and Designs Ref No.: NG/P/2012/639.

has been cited by the following article:

  • TITLE: Medicinal Synthetic Aluminum-Magnesium Silicate {Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3} —A Highly Active Anti-Retroviral Medicine

    AUTHORS: Maduike C. O. Ezeibe, Ijeoma J. Ogbonna

    KEYWORDS: MSAMS-Nanoparticles, Unmasking “Hidden Infections”, Moping-Out HIV, Access to All Organs/Tissues

    JOURNAL NAME: World Journal of AIDS, Vol.6 No.2, April 22, 2016

    ABSTRACT: Medicinal synthetic Aluminum-magnesium silicate (MSAMS), which has inhibited Human immune deficiency virus (HIV), in vitro, was used for trial-treatment of HIV/AIDS patients. Their plasma were tested for viral loads (VL): before and repeatedly during the treatment. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg)and immunace extra protection?. After 4 weeks, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When VL decreased bellow 50/ml, the treatment continued, 4 weeks before stopping. Mean-VL of four patients increased (P = 0.006) from 498.50 ± 33.37 to 1,072.50 ± 184.55, after 3.75±2.06 weeks and decreased (P = 0.040) to 407.33 ± 297.27 (18.29%) when the treatment-duration increased to 6.67 ± 2.31 weeks. Prolonging the duration to 12.00 ± 2.83 weeks led to 98.68% decrease of mean-VL of four other patients, from 24,250.00 ± 15,939.34 to 321.00 ± 229.38(P = 0.045). Two HIV positive persons treated for 4 weeks after their VL reduced bellow 50/ml have remained healthy, 10 and 16 months respectively, without routine antiretroviral medication.