Han, F., Watt, W., Duchamp, D., Callahan, L., Kézdy, F.J. and Agarwal, K. (1990) Molecular Structure of Deoxycytidyl-3’-methylphosphonate (RP) 5’-Deoxyguanidine, d[CP(CH3)G]. A Neutral Dinucleotide with Watson-Crick Base Pairing and a Right Handed Helical Twist. Nucleic Acids Research, 18, 2759-2767.
http://dx.doi.org/10.1093/nar/18.9.2759

has been cited by the following article:

• TITLE: Modified RNA with a Phosphate-Methylated Backbone. A Serious Omission in Our (Retracted) Study at HIV-1 RNA Loops and Integrated DNA. Specific Properties of the (Modified) RNA and DNA Dimers

  AUTHORS: Henk M. Buck

  KEYWORDS: Phosphate-Methylated RNA and DNA, Conformational Study, Replication and Transcription Inhibition, Chemistry of DNA Dimers during Crystallization, 5-Substituted Cytosines in DNA, Conflicting Structural Determinations, Duchenne

  JOURNAL NAME: Journal of Biophysical Chemistry, Vol.7 No.1, February 18, 2016

  ABSTRACT: After the recent publication in the Journal of Biophysical Chemistry entitled “Retracted HIV Study Provides New Information about the Status of the in Vitro Inhibition of DNA Replication by Back-bone Methylation”, it is of importance to review the results of Buck’s group on the synthesis and conformation analyses of phosphate-methylated RNAs in order to afford information on the absence of a further investigation with regard to this de facto acceptable approach. In fact these compounds belong to the very first group of RNAs with a modified neutral backbone by phosphatemethylation. In contrast to the corresponding phosphate-methylated DNAs with a frozen B-conformation, the phosphate-methylated RNAs show an A-conformation. The latter is a prerequisite for duplex formation with (complementary) (natural) RNA. A number of experiments support this fundamental statement. After the HIV study was retracted, the overall results concerning the phosphate-methylated RNAs were published without mentioning Buck’s initial proof of concept and his contributions. Generally, the (modified) dimer RNAs and DNAs possess a number of specific biophysical properties. A novel explanation is given for conflicting structural determinations.