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Article citations


Wolthuis, E.K., Choi, G., Dessing, M.C., Bresser, P., Lutter, R., et al. (2008) Mechanical Ventilation with Lower Tidal Volumes and Positive End-Expiratory Pressure Prevents Pulmonary Inflammation in Patients without Preexisting Lung Injury. Anesthesiology, 108, 46-54.

has been cited by the following article:

  • TITLE: Pressure-Controlled Inverse Ratio Ventilation during General Anesthesia for Open Abdominal Surgery Improves Postoperative Pulmonary Function

    AUTHORS: Xiuqin Wang, Peimin Wang, Kaiguo Wang, Tao Jiang, Zan Xu

    KEYWORDS: Inverse Ratio Ventilation, Conventional Ventilation, General Anesthesia, Lung Function

    JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.9 No.1, January 21, 2016

    ABSTRACT: Background: Studies have shown that pressure-controlled ventilation improves alveolar gas distribution. And inverse ratio ventilation has advantages of improving oxygenation in acute respiratory distress syndrome (ARDS) patients. However, the effects that pressure-controlled inverse ration ventilation in patients undergoes endotracheal intubation general anesthesia have not been assessed. Objective: To investigate whether pressure-controlled inverse ratio ventilation (PIV) would improve ventilatory and oxygenation parameters as well as lung function compared to conventional ventilation in patients undergoing open abdominal surgery. Interventions: In the conventional ventilation (CV) group, the ventilation strategy involved zero end-expiratory pressure and volume-controlled ventilation. In the pressure-controlled inverse ratio ventilation (PIV) group, the strategy involved P high starting at 7 cm H2O, P low starting at 4 cm H2O, T high at 4 s, T low at 2 s, and an inspiratory-to-expiratory time ratio of 2:1. The ΔP value was adjusted according to VT. Pressure levels were increased by 2 cm H2O until a maximal VT was observed. Inspired oxygen fraction (FIO2) was 1.0 and tidal volume (VT) was 6 mL/kg in both groups. Main Outcome Measures: The primary outcome is pulmonary function tests. Hemodynamic, ventilatory and oxygenation parameters were measured; visual analog scale (VAS) scores, and nausea and vomiting scores were also measured. Results: The PIV group tolerated pressure-controlled inverse ratio ventilation without significant hemodynamic instability. Mean airway pressure and static compliance were significantly higher in the PIV group than those in CV group (P P 2 h was well tolerated and improved respiratory compliance and lung function on the first postoperative day.