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Article citations


Hanagasi, H.A., Gurvit, H., Unsalan, P., Horozoglu, H., Tuncer, N., Feyzioglu, A., Gunal, D.I., Yener, G.G., Cakmur, R., Sahin, H.A. and Emre, M. (2011) The Effects of Rasagiline on Cognitive Deficits in Parkinson’s Disease Patients without Dementia: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. Movement Disorders, 26, 1851-1858.

has been cited by the following article:

  • TITLE: Quantitative EEG Changes in Patients with Parkinson’s Disease during Therapy with Rasagiline

    AUTHORS: Wilfried Dimpfel, Christian Oehlwein, Josef Anton Hoffmann, Thomas Müller

    KEYWORDS: Rasagiline, Selegiline, Quantitative EEG, CATEEM®, Parkinson’s Disease, Cognition

    JOURNAL NAME: Advances in Parkinson's Disease, Vol.3 No.3, August 28, 2014

    ABSTRACT: It has been suggested that in patients with Parkinson’s disease (PD) metabolism of the MAO-B inhibitor selegiline to methamphetamine may contribute and/or exacerbate sleep problems, possibly leading to deficits of cognition. This open-label exploratory study included 30 PD patients currently being treated with selegiline (7.5 mg/day) and complaining of sleep disturbances. The aim of the study was to determine whether switching from selegiline to another MAO-B inhibitor without amphetamine-like metabolites, namely rasagiline, would improve sleep behaviour and cognitive function in PD patients. Pathologic aberrations as determined by comparison of the frequency pattern of patients to a database consisting of healthy subjects revealed an approximation of electric brain activity to normality. For verification of efficacy, a combination of questionnaires, quantitative source density EEG recording with CATEEMò and performance of two psychometric tasks (d2-test of attention and reading) during the EEG recording were done on the last day of selegiline treatment (7.5 mg/day) as well as 2 and 4 months later, during which the patients were treated with rasagiline (1 mg/day). In addition, performance of the mental tasks revealed a statistically significant (p