TITLE:
Review on Molecular Typing Methods of Pathogens
AUTHORS:
Tiehao Lin, Liying Lin, Fan Zhang
KEYWORDS:
Pathgens, Bacterial Typing Techniques, Pharmaceutical
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.4 No.3,
July
11,
2014
ABSTRACT:
This paper presents several common molecular typing methods, Pulsed-Field Gel Electrophoresis (PFGE), Restriction Fragment Length Polymorphisma (RFLP), Random Amplified Polymorphic DNA (RAPD), Automatic Ribotyping, rep-PCR, Multi-Locus Sequence Typing (MLST), in which the application and progress of molecular typing of pathgens for these methods are described. These methods played an important role in pathgens source tracking, knowing the source(s) of bacteria in pharmaceutical, preventing and controlling the diarrhea and food-poisoning outbreaks, which have great value in the remediation and prevention of further bacterial contamination.