TITLE:
Antidermatophytic Activity of Essential Oils against Locally Isolated Microsporum canis—Gaza Strip
AUTHORS:
Emad Khalil Abou Elkhair
KEYWORDS:
Antifungal, Microsporum canis, Mentha piperta, Essential Oils, Gaza Strip
JOURNAL NAME:
Natural Science,
Vol.6 No.9,
May
29,
2014
ABSTRACT:
There is a need for
new antimicrobial drugs due to the continuous development of resistance. Natural
antimicrobials are of utmost importance due to safety issue and availability. The antifungal activity of four
essential oils (Mentha piperta, Thymus vulgaris, Cymbopogon citratus, and Oreganum majoranum oils)
against locally isolated Microsporum canis was determined by disc
diffusion method and minimum inhibitory concentration was determined using
broth dilution method. Mentha piperta oil showed the highest antifungal
activity among tested oils in this study. The total inhibition attached when
0.046% was used with M. piperta, the total inhibition obtained with the
0.133% of C. citratus oil, which is accounted as the second essential oils,
also T. vulgaris and O. majoranum oils achieved reductions at
0.133%. The present work has revealed that all oils have been used in low
concentrations and produced promising results in comparison to the positive
control (Clotrimazole).