Fraser Syndrome: Case Report with Review of Literature

Saruban Pasu, Luna Dhir, Sarah Mackenzie, Graham Thompson
DOI: 10.4236/ojoph.2011.11001                

Abstract

Fraser syndrome is a rare autosomal recessive multisystem disorder with a reported incidence of 0.043 per 10,000 live born infants and 1.1 in 10,000 stillbirths[1]. The condition is characterised by cryptophthalmos, cutaneous syndactyly, laryngeal and genitourinary malformations, craniofacial dysmorphism, orofacial clefting, musculoskeletal anomalies and mental retardation. The diagnosis can be made on prenatal scans, post natal clinical examination or on autopsy findings. We present a case of Fraser syndrome and review of the ocular manifestations of this condition.

Keywords

Cryptophthalmos, Fraser Syndrome

Conflicts of Interest

The authors declare no conflicts of interest.

References

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