Calibrating volume measurements made using the dual-field conductance catheter
Simon P. McGuirk, David Barron, Dan Ewert, John H. Coote
DOI: 10.4236/jbise.2009.27070   PDF    HTML     4,747 Downloads   8,592 Views   Citations


The conductance catheter technique allows real- time measurements of ventricular volume based on changes in the electrical conductance of blood within the ventricular cavity. Conductance volume measurements are corrected with a calibration coefficient, α, in order to improve accuracy. However, conductance volume measurements are also affected by parallel conductance, which may confound cali-bration coefficient estimation. This study was un-dertaken to examine the variation in α using a physical model of the left ventricle without parallel conductance. Calibration coefficients were calculated as the conductance-volume quotient (αV(t)) or the stroke conductance-stroke volume quotient (αSV). Both calibration coefficients varied as a non-linear function of the ventricular volume. Conductance volume measurements calibrated with αV(t) estimated ventricular volume to within 2.0 ± 6.9%. By contrast, calibration with αSV substantially over-estimated the ventricular volume in a volume-dependent manner, increasing from 26 ± 20% at 100ml to 106 ± 36% at 500ml. The accuracy of conductance volume measurements is affected by the choice of calibration coefficient. Using a fixed or constant calibration coeffi-cient will result in volume measurement errors. The conductance-stroke volume quotient is associated with particularly significant and volume-dependent measurement errors. For this reason, conductance volume measurements should ideally be calibrated with an alternative measurement of ventricular vol-ume.

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P. McGuirk, S. , Barron, D. , Ewert, D. and H. Coote, J. (2009) Calibrating volume measurements made using the dual-field conductance catheter. Journal of Biomedical Science and Engineering, 2, 484-490. doi: 10.4236/jbise.2009.27070.

Conflicts of Interest

The authors declare no conflicts of interest.


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