Entropy Production Rate for Avascular Tumor Growth
Elena Izquierdo-Kulich, Esther Alonso-Becerra, José M Nieto-Villar
DOI: 10.4236/jmp.2011.226071   PDF    HTML     5,918 Downloads   10,303 Views   Citations


The entropy production rate was determined for avascular tumor growth. The proposed formula relates the fractal dimension of the tumor contour with the quotient between mitosis and apoptosis rate, which can be used to characterize the degree of proliferation of tumor cells. The entropy production rate was determined for fourteen tumor cell lines as a physical function of cancer robustness. The entropy production rate is a hallmark that allows us the possibility of prognosis of tumor proliferation and invasion capacities, key fac-tors to improve cancer therapy.

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E. Izquierdo-Kulich, E. Alonso-Becerra and J. Nieto-Villar, "Entropy Production Rate for Avascular Tumor Growth," Journal of Modern Physics, Vol. 2 No. 6A, 2011, pp. 615-620. doi: 10.4236/jmp.2011.226071.

Conflicts of Interest

The authors declare no conflicts of interest.


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