Resolution of Alcohol Racemate by Oil
Adi Wolfson, Nadia Komyagina, Christina Dlugy, Janine Blumenfeld
DOI: 10.4236/gsc.2011.11002   PDF    HTML     6,349 Downloads   11,906 Views   Citations


Vegetable oil was successfully used as solvent and acyl donor in the kinetic resolution of several secondary alcohol racemates yielding high enantioselectivities. Using vegetable oil as solvent and acyl donor allowed easy separation of the pure alcohol enantiomer by extraction with methanol, by distillation under reduced pressure, or by column chromatography.

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A. Wolfson, N. Komyagina, C. Dlugy and J. Blumenfeld, "Resolution of Alcohol Racemate by Oil," Green and Sustainable Chemistry, Vol. 1 No. 1, 2011, pp. 7-11. doi: 10.4236/gsc.2011.11002.

Conflicts of Interest

The authors declare no conflicts of interest.


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