Garlic Clove Catalyzed Biginelli Reaction in Water at Ambient Temperature

Hishame Abd-Elnabi, Afaf Mohamed Abdel Hameed, Ramadan Ahmed Mekheimer, Reham R. Awed, Kamal Usef Sadek

Department of Chemistry, Faculty of Science, El-Minia University, El-Minia, Egypt.
Department of Chemistry, Faculty of Science, El-Minia University, El-Minia, Egypt; Department of Chemistry, Faculty of Science for Girls, King Abdulaziz University, Jeddah, KSA.

DOI: 10.4236/gsc.2013.34017                

Abstract

A simple, green and highly efficient procedure for the Biginelli condensation reaction of aldehydes, β-ketoesters, urea or thiourea catalyzed by crushed garlic clove at ambient temperature is reported.

Keywords

Garlic Glove; Biocatalysis; Water; Biginelli Reaction

Conflicts of Interest

The authors declare no conflicts of interest.

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