When the skin meets the bowel: About a case

Ganzetti Giulia, Campanati Anna, Di Sario Antonio, Rubini Corrado, Zizzi Antonio, Tarantino Giuseppe, Benedetti Antonio, Offidani Annamaria

Anatomic Pathology Institute, Department of Neurosciences, Polytechnic University of Marche, Ancona, Italy.
Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy.
Gastroenterologic Clinic, Department of Clinical and Molecular Medicine, Polytechnic Marche University, Ancona, Italy.

DOI: 10.4236/ojgas.2013.36052                

Abstract

Ulcerative colitis (UC) is a chronic relapsing inflammatory disease of the colorectal region which may be complicated by extraintestinal manifestations, as cutaneous involvement. Immune dysregulation resulting in a lymphocyte mediated destructive process has been suggested as a possible pathogenetic link between gut and skin-related manifestations. The authors describe an atypical clinical aspect of lichen ruber planus in a patient affected by vitiligo, alopecia areata and ulcerative colitis.

Keywords

Ulcerative Colitis; Vitiligo; Lichen Ruber Planus; Alopecia Areata; Autoimmunity

Conflicts of Interest

The authors declare no conflicts of interest.

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