Necrotising stomatitis as a presenting symptom of HIV
Gbemisola A. Agbelusi, Olutola M. Eweka
DOI: 10.4236/ojst.2011.14025   PDF   HTML     3,779 Downloads   6,895 Views   Citations


Background: Necrotising Stomatitis is an uncommon oral infection associated with diminished systemic resistance (immunocompromised state) including HIV infection. Significant predisposing factors include poor oral hygiene, unusual life stress, recent illness (e.g. Measles), malnutrition, smoking and even inade- quate sleep. It occurs commonly in developing na-tions with poor living conditions. Objective: To present a case of severe Necrotising Stomatitis in a previously undiagnosed HIV Seropositive patient. Patient and method: This case report describes severe, rapidly spreading necrotising stomatitis in a 35 years old lady, the condition which led to her being diagnosed with HIV. The treatment modalities, challenges of man-agement and the differential diagnosis were discussed. Result: During the course of her management, pa-tient’s oral condition improved. However, later re-currence was seen due to severe anaemia caused by malnutrition and aggravated by Zidovudine antiret-roviral drug. Conclusions: There is need for interdis-ciplinary interactions between the dentists and the physicians managing HIV patients, to allow effective management and afford patient the best treatment.

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Agbelusi, G. and Eweka, O. (2011) Necrotising stomatitis as a presenting symptom of HIV. Open Journal of Stomatology, 1, 168-171. doi: 10.4236/ojst.2011.14025.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Buchanan, J.A.G., Cedro, M., Mirdin, A., Joseph, T., Porter, S.R. and Hodgson, T.A. (2006) Necrotising stomatitis in the developed world. Clinical and Experimental Dermatology, 31, 372-374. doi:10.1111/j.1365-2230.2006.02067.x
[2] Heddie, O.S. (2006) Frequent oral diseases in HIV positive and AIDS patients. Clinical and Experimental Dermatology, 31, 372-374.
[3] Horning, G.M. and Cohen, M.E. (1995) Necrotising ulcerative gingivitis, periodontitis and stomatitis: Clinical staging and predisposing factors. Journal of Periodontology, 66, 990-998.
[4] American Academy of Periodontology (2000) Parameter on acute periodontal diseases. Journal of Periodontology, 71, 863-866. doi:10.1902/jop.2000.71.5-S.863
[5] Wright, A.A. and Agbelusi, G.A. (2005) Group II and III lesions in HIV positive Nigerians attending the General Hospital Lagos, Nigeria. Odontostomatologic Tropicale, 28, 19-23.
[6] Agbelusi, G.A. and Wright, A.A. (2005) Oral lesions as indicators of HIV infection among routine dental patients in Lagos, Nigeria. Oral diseases, 11, 370-373. doi:10.1111/j.1601-0825.2005.01132.x
[7] Anteyi, K.O., Thacher, T.D., Yohanna, S. and Idoko, J.I. (2003) Oral manifestation of HIV/AIDS in Nigerian patients. International Journal of STD & AIDS, 14, 395- 398. doi:10.1258/095646203765371286
[8] Onunu, A.N. and Obueke, N. (2002) HIV-related oral diseases in Benin City, Nigeria. West African Journal of Medicine, 21, 9-11.
[9] Neville, B.W., Damn, D.D., Allen, C.M. and Bouquot, J.E. (2002) Oral and Maxillofacial pathology. W. B. Saunders, Philadelphia, 513-519.
[10] Greenspan, J.S., Barr, C.E., Scuibba, J.J. and Winkler, J.R., (1992) USA Oral AIDS Collaboration Group. Oral manifestations of HIV infection: Definitions, diagnostic criteria and principles of therapy. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, 73, 142-144.

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