Eco-friendly Synthesis of Cyclododecanone from Cyclododecatriene

DOI: 10.4236/gsc.2011.13011   PDF   HTML     6,152 Downloads   11,523 Views   Citations


An eco-friendly synthesis of cyclododecanone (CDON) from cyclododecatriene (CDT) is described. Selec- tive epoxidation of CDT with hydrogen peroxide using hexadecyl trimethyl ammonium heteropolyphospha- totungstate [(n-C16H33NMe3)3PW4O16, HAHPT] as catalyst and water as solvent followed by the hydrogena- tion on Raney nickel catalyst gave cyclododecanol (CDOL). The latter was oxidized with hydrogen peroxide using HAHPT as catalyst and a mixture of water and t-butanol as solvent to afford CDON. The total yield was 53.4% under the optimum reaction conditions.

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Q. Feng, D. Yuan, D. Wang, X. Liang, J. Zhang, J. Wu and F. Chen, "Eco-friendly Synthesis of Cyclododecanone from Cyclododecatriene," Green and Sustainable Chemistry, Vol. 1 No. 3, 2011, pp. 63-69. doi: 10.4236/gsc.2011.13011.

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The authors declare no conflicts of interest.


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