Recent Research Progress on Study of Paragonimus westermani in China

Dingli Xu; Jing Li; Qi Liao; Tuergong Jiang; Jiang Cai; Yuelong Lv; Jiakuan Lv; Baile Shen; Zexian Xu; Yanting Zhang; Jianfa Liu

doi:10.4236/oalib.1101511

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Open Access Library Journal > Vol.2 No.5, May 2015

Recent Research Progress on Study of Paragonimus westermani in China ()

Dingli Xu, Jing Li, Qi Liao, Tuergong Jiang, Jiang Cai, Yuelong Lv, Jiakuan Lv, Baile Shen, Zexian Xu, Yanting Zhang, Jianfa Liu^*

Ningbo University School of Medicine, Ningbo, China.

DOI: 10.4236/oalib.1101511 PDF HTML XML 902 Downloads 1,468 Views

Abstract

Recently, along with the development of biochemical and molecular immunological techniques, the diagnosis methods have been improved in which preparing natural parasite antigens, and genetically engineered recombinant antigens have been applied by using agglutination test, complement fixation methods to detect the human’s serum antibodies for parasite identification of paragonimus infections. To improve the detection rate, some scholars have used phage peptide library technology to further improve the diagnostic effect on Paragonimus westermani in humans. In this paper, we summarized recent studies on diagnosis, pathogenesis and treatment of Paragonimus flukes in China.

Keywords

Paragonimus westermani, Antigen, Phage Peptide Library Technology, China

Share and Cite:

Xu, D. , Li, J. , Liao, Q. , Jiang, T. , Cai, J. , Lv, Y. , Lv, J. , Shen, B. , Xu, Z. , Zhang, Y. and Liu, J. (2015) Recent Research Progress on Study of Paragonimus westermani in China. Open Access Library Journal, 2, 1-4. doi: 10.4236/oalib.1101511.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Chen, S.H., Zhou, X.-N. and Zhang, Y.-N. (2007) Dynamics of Specific Antibody and Circulating Antigen in Sera from the Dogs Infected with Paragonimus westerman. Chinese Journal of Veterinary Parasitology, 15, 11-14.
[2]	Chen, Q.J. and Yin, J.-G. (2007) Chin Research and Perspectives in Parasitology. Chinese Journal of Parasitology & Parasitic Diseases, 25, 344-348.
[3]	Zhang, D., Wang, Z.Q. and Cui, J. (2003) The Specific Diagnostic Antigens of Paragonimus westermani Adult Worms. The Jounal of Zhenzhou University, 38, 538-540.
[4]	Li, T.-Q., Jiang, C.-F. and Shi, H.-B. (2005) Observation on the Immuno-Reactivity of the Mimic Antigen Epitope of Paragonimus westermani. Chinese Journal of Zoonoses, 21, 507-509.
[5]	Chen, S.-H., Li, H. and Zhou, X.-N. (2007) Establishment and Application of Circulating Antigen Detection in Paragonimus westermani Infection. Chinese Journal of Parasitology & Parasitic Diseases, 25, 513-514.
[6]	Lin, Z.-G., Li, Y.-S. and Zhang, Z.-P. (2003) Investigation on Paragonimiasis in Yanping County of Fujian Province. Journal of Tropical Diseases and Parasitology, 1, 135-137.
[7]	Ji, H.-J. and Wang, H., ( 2012) The Diagnosis and Treatment of Pleural Effusion of Paragonimiasis. Journal of Clinical Pulmonary Medicine, 17, 1872-1874.
[8]	Tong. D.S., Liu, Y.X. and Tang, F. (2013) Detection of Four Parasitic Infections Using ELISA. Chinese Journal of Schistosomiasis Control, 25, 327-328.
[9]	Ma, A., Shi, X.-H., Wang, Y. and Gan, X.-X. (2005) Development and Application of Rapid Detection in Specific IgG4 of Paragonimiasis. Chinese Journal of Zoonoses, 26, 353-355.
[10]	Niu, J.-X., Zhang, X.-L. and He, X. (2010) Adult Antigens of Pagumogonimus skrjabini Identified by the Serum with Paragonimiasis and Analysis on Their Characterizations. International Journal of Medical Parasitic Disease, 37, 136-140.
[11]	Lin, J.-J., Zhang, Z.-H. and Zhang, Y.J. (2002) Immunoscreening of Paragonimus westermani Adult cDNA Library Using Monoclone Antibodies. Chinese Journal of Zoonoses, 18, 48-53.
[12]	Liu, J.-N., Ling, J.-J., Hou, M., Zhang, Z.-H. and Zhang, Y.-J. (2003) The Experience and Identification of Paragonimlasis westermani Adult Recombinant Antigen. Chinese Journal of Parasitology and Parasitic Disease, 16, 96-98.
[13]	Lei, J.-H., Jiang, C.-F. and Li, T.-Q. (2004) Comparing the Antigenicty of Two Kinds of Antigen-Mimic Epitopes of Paragonimus westermani Screened from the 12-Mer Phage Peptide Library Used Different Methods. Journal of Tropical Diseases and Parasitology, 2, 3-6.
[14]	Liu, J.-F., Zhang, J.-N. and Jiang, W.-W. (2013) Advance in Comparative Study on Diploid and Tripoid of Paragonimus wastermani. Chinese Journal of Zoonoses, 29, 191-194.
[15]	Zhao, X., Zheng, Q.-Y., Cao, J.-J. and Zhao, Q.-C. (2008) Detection of Paragonimus westemrani by PCR and Real-Time PCR. Biotechnology Bulletin, S1, 359-361.