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Late Onset Neonatal Herpes Encephalitis: A Case-Based CNS Complication and Neurological Outcome

DOI: 10.4236/oalib.1101280    352 Downloads   621 Views   Citations

ABSTRACT

Individual neurological complication caused by Herpes simplex viruses in neonates is well-known. We report neonatal Herpes encephalitis that caused multiple neurological complications in the same patient during acute phase of illness. Our patient differs from previously reported cases in the following ways: 1) Late onset neonatal presentation; 2) Development of multiple neurologic complications during acyclovir therapy; 3) Cesarean-section did not prevent perinatal transmission of Herpes simplex virus; and 4) Our patient’s acute hydrocephalus was managed conservatively and he had no reoccurrence of seizure, hydrocephalus, and no motor deficits. A high degree of suspicion, timely needed supportive medical and surgical care, and prompt initiation of intravenous acyclovir offer the best chance for neurological outcome in neonates with Herpes encephalitis.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Gupta, S. , Gupta, V. and Borad, N. (2015) Late Onset Neonatal Herpes Encephalitis: A Case-Based CNS Complication and Neurological Outcome. Open Access Library Journal, 2, 1-7. doi: 10.4236/oalib.1101280.

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