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NMR-Relaxometer for Diagnosis and Control of Chronic Kidney Disease Patients Parameters (Urea and Creatinine)

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DOI: 10.4236/oalib.1101151    1,832 Downloads   2,071 Views   Citations

ABSTRACT

Determination of disease stages and control of changes in blood and plasma during kidney injury (KJ) cure can be done using nuclear (proton) magnetic resonance (NMR) parameters dependences from physical-chemical parameters of blood changes. NMR spectroscopy allows the monitoring of molecular recognition processes in solution. For realization of this approach the low field NMR relaxometer was elaborated. Measurements of relaxation parameters were performed. Dependences of relaxation times Т2А from urea and serum creatinine were received.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Kashaev, R. and Khaziahmetova, L. (2014) NMR-Relaxometer for Diagnosis and Control of Chronic Kidney Disease Patients Parameters (Urea and Creatinine). Open Access Library Journal, 1, 1-5. doi: 10.4236/oalib.1101151.

References

[1] Chertow, G.M., Burdick, E., Honour, M., Bonventre, J.V. and Bates, D.W. (2005) Acute Kidney Injury, Mortality, Length of Stay, and Costs in Hospital Patients. Journal of the American Society of Nephrology, 16, 3365-3370.
http://dx.doi.org/10.1681/ASN.2004090740
[2] Bellomo, R., Ronco, C., Kellum, J.A., Mehta, R.L. and Palevsky, P. (2004) Acute Renal Failure—Definition, Outcome Measures, Animal Models, Fluid Therapy and Information Technology Needs: The Second International Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Critical Care, 8, R204-R212.
http://dx.doi.org/10.1186/cc2872
[3] Unione, L., Galante, S., Diaz, D, Canada, F.J. and Barbero, J.J. (2014) NMR and Molecular Recognition. The Application of Ligand-Based NMR-Methods to Monitor Molecular Interactions. Medicinal Chemistry Communications, 5, 1280-1289.
http://dx.doi.org/10.1039/C4MD00138A
[4] Kashaev, R.S., Idiatullin, Z.Sh. and Temnikov, A.N. (2007) Portable Relaxometer NMR. RF Patent No. 67719, Bulletins of Inventions No. 30.
[5] Kashaev, R.S., Idiatullin, Z.Sh. and Temnikov, A.N. (2008) Device for Thermostating of Sample in the NMR Probehead. Patent of RF No. 2319138, Bulletins of Inventions No. 32.
[6] Meiboom, S. and Gill, D. (1958) Modified Spin-Echo Method for Measuring Nuclear Relaxation Times. Review of Scientific Instruments, 29, 688-691.

  
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