First Masquerading as Gallstones, Pulmonary Hypertension Mimics PE


Patients presenting to emergency and urgent care centers with calf pain after long and short-haul flights are a common presentation throughout Europe. Patients fitting an epidemiological risk profile for cholelithiasis and presenting with right upper quadrant abdominal pain can also be a common presentation fitting of a specific patient profile. However, pulmonary hypertension can present in a nuanced and possible missed chronic and acute presentation. The patient case we present profiles a mildly obese 54-year-old Caucasian woman and recent holiday maker with unilateral calf pain and shortness of breath after traveling on a long-haul flight with tertiary symptoms of indigestion and epigastric discomfort indicative of gastroenteritis. This case highlights the required diligence for emergency physicians to maintain a high index of suspicion and broad differential diagnosis in the undifferentiated patient with seemingly common or classic presentations. We find that a serendipitous definitive diagnosis is made by following a systematic and organized approach.

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Quinn, J. , Ukwatta, S. , Luke, C. , Zeleny, T. and Bencko, V. (2015) First Masquerading as Gallstones, Pulmonary Hypertension Mimics PE. Case Reports in Clinical Medicine, 4, 376-380. doi: 10.4236/crcm.2015.412076.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Cruickshank, J.M., Gorlin, R. and Jennett, B. (1988) Air Travel and Thrombotic Episodes: The Economy Class Syndrome. Lancet, 2, 497-498.
[2] Beasley, R., Heuser, P. and Raymond, N. (2005) SIT (Seated Immobility Thromboembolism) Syndrome: A 21st Century Lifestyle Hazard. The New Zealand Medical Journal, 118, U1376.
[3] Chang, H.-C.L., Burbridge, H. and Wong, C. (2013) Extensive Deep Vein Thrombosis Following Prolonged Gaming (“Gamers Thrombosis”): A Case Report. Journal of Medical Case Reports, 7, 235.
[4] Everhart, J.E., Khare, M., Hill, M. and Maurer, K.R. (1999) Prevalence and Ethnic Differences in Gallbladder Disease in the United States. Gastroenterology, 117, 632-639.
[5] National Pulmonary Hypertension Centres of the UK and Ireland (2008) Consensus Statement on the Management of Pulmonary Hypertension in Clinical Practice in the UK and Ireland. Heart, 94, i1-i41.
[6] Anning, S.T. (1957) The Historical Aspects of Venous Thrombosis. Medical History, 1, 28-37.
[7] Beasley, R., Raymond, N., Hill, S., Nowitz, M. and Hughes, R. (2003) eThrombosis: The 21st Century Variant of Venous Thromboembolism Associated with Immobility. European Respiratory Journal, 21, 374-376.
[8] Kearon, C. (2013) Chapter 6, the Respiratory System. In: Bope, E.T. and Kellerman, R.D., Eds., Conn’s Current Therapy 2013, Saunders, 327-361.
[9] Diehl, A.K. (1991) Epidemiology and Natural History of Gallstone Disease. Gastroenterology Clinics of North America, 20, 1-19.
[10] McLaughlin, V.V. and McGoon, M.D. (2006) Pulmonary Arterial Hypertension. Circulation, 114, 1417-1431.

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