New Schiff Bases from 6,6’-Diformyl-2,2’-Bipyridyl with Amines Containing O, S, N and F: Synthesis and Characterization

Md. Razzak¹, Mohammad R. Karim^2*, Md. Rejaul Hoq¹, Aminul H. Mirza²

¹Department of Chemistry, Tennessee State University, Nashville, USA.
²Department of Chemistry, Faculty of Science, Universiti Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam.

DOI: 10.4236/ijoc.2015.54026                

Abstract

Eight novel Schiff Bases, from 6,6′-diformyl-2,2′-bipyridyl (1a, 43%)with O, N, S and F containing amines: Thiosemicarbazide (2a, 70%), 4-Ethyl-3-thiosemicabazide (2b, 75%), 4,4-Dimethyl-3-thio-semicarbazide (2c, 75%), S-benzyldithiocarbazide, SBDTC (2d, 80%), (Trifluromethyl) phenylhy-drazine (2e, 80%), 4-Phenyl-3-thiosemcarbazide (2f, 80%), Thiocarbazide (2g, 70%), 2-Amino-thiophenol (2h, 65%), have been synthesized. The conventional method of synthesis of the Schiff bases involves refluxing the reaction mixture containing the diformyls and amines for 1 hour. The solid products that had formed were filtered off using suction filtration. In few reactions, 2 - 3 drops of conc. sulfuric acid were used to obtain high yield. The structures of all eight novel synthesized compounds have fully been characterized by spectroscopic (IR, NMR, MS) methods.

Keywords

2, 2’-Bipyridyl, Schiff Base, O, N, S and F Containing Amines, 6, 6’-Diformyl

Conflicts of Interest

The authors declare no conflicts of interest.

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