Allergies in Children: What’s New?—A Cross-Sectional Descriptive Study

Abstract

Background: The prevalence of respiratory allergies is increasing worldwide, with important consequences especially for little children. Objective: The aim of this study was to assess the prevalence of respiratory allergies, such as rhinitis and asthma, and to point out the risk factors and their relationship with allergic diseases in a specific area of Northern Italy. Methods: 110 children, male and female, from our outpatient service for allergic children, between 3 and 17 years old, were examined. After a skin prick test and a nasal cytology, the written questionnaire of the International Study of Asthma and Allergies in Childhood was filled by parents together with their children. Results: 110 children were examined. 74% of children had rhinitis and 71% asthma. 88 patients were allergic, grass pollen and house dust mite was the most frequent allergens. A family history of atopy, family background, geographic area, active and passive smoking and home pets were associated to allergies. Older children (6 - 15 years old) had more often rhinitis associated with asthma and conjunctivitis as compared to younger. 21 Children were also affected by non allergic rhinitis. Conclusions: Respiratory allergies are widespread and associated to a low quality of life among little children. Sensitization to Ragweed is increasing with important consequences. Rhinitis precedes the onset of asthmatic symptoms. Moreover non allergic rhinitis is increasing and frequently underdiagnosed.

Share and Cite:

Simoncini, D. , Peirolo, A. , Macchi, A. , Porcu, S. , Graziani, D. and Nespoli, L. (2015) Allergies in Children: What’s New?—A Cross-Sectional Descriptive Study. Open Journal of Pediatrics, 5, 296-303. doi: 10.4236/ojped.2015.54045.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] A European Declaration on Allergen Immunotherapy. The European Academy of Allergy and Clinical Immunology (EAACI) 2011.
http://www.eaaci.org/372-resources/immunotherapy-declaration.html
[2] Ring, J. (2012) Davos Declaration: Allergy as a Global Problem. Allergy, 67, 141-143.
http://dx.doi.org/10.1111/j.1398-9995.2011.02770.x
[3] Bousquet, J., Schünemann, H.J., Samolinski, B., et al. (2012) Allergic Rhinitis and Its Impact on Asthma (ARIA): Achievements in 10 Years and Future Needs. Journal of Allergy and Clinical Immunology, 130, 1049-1062.
http://dx.doi.org/10.1016/j.jaci.2012.07.053
[4] Valovirta, E. (2011) EFA Book on Respiratory Allergies: Raise Awareness, Relieve the Burden.
http://www.efanet.org
[5] Keil, T., Bockelbronk, A., Reich, A., et al. (2010) The Natural History of Allergic Rhinitis in Childhood. Pediatric Allergy and Immunology, 21, 962-969.
http://dx.doi.org/10.1111/j.1399-3038.2010.01046.x
[6] Peroni, D.G., Piacentini, G.L., Alfonsi, L., et al. (2003) Rhinitis in Pre-School Children: Prevalence, Association with Allergic Diseases and Risk Factors. Clinical & Experimental Allergy, 33, 1349-1354.
http://dx.doi.org/10.1046/j.1365-2222.2003.01766.x
[7] Bousquet, J., Heinzerling, L., Bachert, C., et al. (2012) Practical Guide to Skin Prick Tests in Allergy to Aeroallergens. Allergy, 67, 18-24.
http://dx.doi.org/10.1111/j.1398-9995.2011.02728.x
[8] Gelardi, M., Fiorella, M.L., Leo, G. and Incorvaia, C. (2007) Cytology in the Diagnosis of Rhinosinusitis. Pediatric Allergy and Immunology, 18, 50-52.
http://dx.doi.org/10.1111/j.1399-3038.2007.00634.x
[9] The International Study of Asthma and Allergies in Childhood, 2012.
http://isaac.auckland.ac.nz/
[10] Tosi, A., Wüthrich, B., Bonini, M. and Pietragalla-Kohler, B. (2011) Time Lag between Ambrosia Sensitisation and Ambrosia Allergy: A 20-Year Study (1989-2008) in Legnano, Northern Italy. Swiss Medical Weekly, 9 October 2011, 141:w13253.
[11] Asero, R. (2012) Ragweed Allergy in Northern Italy: Are Patterns of Sensitization Changing? European Annals of Allergy and Clinical Immunology, 44, 157-159.
[12] Morais-Almeida, M., Santos, N., Pereira, A.M., Branco-Ferreira, M., Nunes, C., Bousquet, J. and Fonseca, J.A. (2013) Prevalence and Classification of Rhinitis in Preschool Children in Portugal: A Nationalwide Study. Allergy, 68, 1278-1288.
http://dx.doi.org/10.1111/all.12221
[13] Wright, A.L., Holberg, C.J., Martinez, F.D., Halonen, M., Morgan, W. and Taussig, L.M. (1994) Epidemiology of Physician-Diagnosed Allergic Rhinitis in Childhood. Pediatrics, 94, 895-901.
[14] Fuertes, E., Butland, B.K., Ross Anderson, H., Carlsten, C., Strachan, D.P. and Brauer, M., ISAAC Phase Three Study Group (2014) Childhood Intermittent and Persistent Rhinitis Prevalence and Climate and Vegetation: A Global Ecologic Analysis. Annals of Allergy, Asthma & Immunology, 113, 386-392.e9.
http://dx.doi.org/10.1016/j.anai.2014.06.021
[15] Stafoggia, M., Cesaroni, G., Galassi, C., Badaloni, C. and Forastiere, F. (2014) Long-Term Health Effects of Air Pollution: Results of the European Project ESCAPE. Recenti Progressi in Medicina, 105, 450-453.
[16] Di Menno di Bucchianico, A., Cattani, G., Gaeta, A., Caricchia, A.M., Troiano, F., Sozzi, R., et al. (2014) Air Pollution in an Urban Area nearby the Rome-Ciampino City Airport. Epidemiologia & Prevenzione, 38, 244-253.
[17] Genuneit, J. (2012) Exposure to Farming Environments in Childhood and Asthma and Wheeze in Rural Populations: A Systematic Review with Meta-Analysis. Pediatric Allergy and Immunology, 23, 509-518.
http://dx.doi.org/10.1111/j.1399-3038.2012.01312.x
[18] Von Mutius, E. and Vercelli, D. (2010) Farm Living: Effects on Childhood Asthma and Allergy. Nature Reviews Immunology, 10, 861-868.
http://dx.doi.org/10.1038/nri2871
[19] Genuneit, J., Strachan, D.P., Büchele, G., Weber, J., Loss, G., Sozanska, B., et al. (2013) The Combined Effects of Family Size and Farm Exposure on Childhood Hay Fever and Atopy. Pediatric Allergy and Immunology, 24, 293-298.
http://dx.doi.org/10.1111/pai.12053
[20] Foliaki, S., Pearce, N., Bjorksten, B., Mallol, J., Montefort, S., von Mutius, E. and the International Study of Asthma and Allergies in Childhood Phase III Study Group (2009) Antibiotics Use in Infancy and Symptoms of Asthma, Rhinoconjunctivitis, and Eczema in Children 6 and 7 Years Old: International Study of Asthma and Allergies in Childhood Phase III. Journal of Allergy and Clinical Immunology, 124, 982-989.
http://dx.doi.org/10.1016/j.jaci.2009.08.017
[21] Gagliardi, L., Rusconi, F., Galassi, C. and Forastiere, F. (2011) Re.: “Antibiotic Exposure by 6 Months and Asthma and Allergy at 6 Years: Findings in a Cohort of 1,401 US Children”. American Journal of Epidemiology, 173, 1343.
http://dx.doi.org/10.1093/aje/kwr082
[22] Rusconi, F., Gagliardi, L., Galassi, C., Forastiere, F., Brunetti, L., La Grutta, S., Piffer, S. and Talassi, F., SIDRIA-2 Collaborative Group (2011) Paracetamol and Antibiotics in Childhood and Subsequent Development of Wheezing/Asthma: Association or Causation? International Journal of Epidemiology, 40, 662-667.
http://dx.doi.org/10.1093/ije/dyq263
[23] Agabiti, N., Mallone, S., Forastiere, F., Corbo, G.M., Ferro, S., Renzoni, E., et al. (1999) The Impact of Parental Smoking on Asthma and Wheezing. SIDRIA Collaborative Group. Studi Italiani sui Disturbi Respiratori nell’Infanzia e l’Ambiente. Epidemiology, 10, 692-698.
http://dx.doi.org/10.1097/00001648-199911000-00008
[24] Virkkula, P., Liukkonen, K., Suomalainen, A.K., Aronen, E.T., Kirjavainen, T. and Pitkaranta, A. (2011) Parental Smoking Nasal Resistance and Rhinitis in Children. Acta Paediatrica, 100, 1234-1238.
http://dx.doi.org/10.1111/j.1651-2227.2011.02240.x
[25] Landau, L.I. (2001) Parental Smoking: Asthma and Wheezing Illnesses in Infants and Children. Paediatric Respiratory Reviews, 2, 202-206.
http://dx.doi.org/10.1053/prrv.2001.0141
[26] Silvestri, M., Franchi, S., Pistorio, A., Petecchia, L. and Rusconi, F. (2015) Smoke Exposure, Wheezing, and Asthma Development: A Systematic Review and Meta-Analysis in Unselected Birth Cohorts. Pediatric Pulmonology, 50, 353-362.
http://dx.doi.org/10.1002/ppul.23037
[27] Molgaard, E., Thomsen, S.F., Lund, T., Pedersen, L., Nolte, H. and Backer, V. (2007) Differences between Allergic and Nonallergic Rhinitis in a Large Sample of Adolescents and Adults. Allergy, 62, 1033-1037.
http://dx.doi.org/10.1111/j.1398-9995.2007.01355.x

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.