The Benefit of Education and Appropriate Antibiotics Use to Reduce Multidrug-Resistant Acinetobacter baumanii in a University-Affiliated Intensive Care Unit in Indonesia

  Cucunawangsih¹, Leni Lukman¹, R. Sariwijaya¹, P. Wibowo², V. Sungono³

¹Department of Microbiology, Faculty of Medicine, University of Pelita Harapan, Tangerang, Indonesia.
²Intensive Care Unit, Siloam General Hospital, Tangerang, Indonesia.
³Department of Public Health, Faculty of Medicine, University of Pelita Harapan, Tangerang, Indonesia.

DOI: 10.4236/ojmm.2015.54020                

Abstract

Acinetobacter baumanii is an opportunistic pathogen known to cause hospital acquired infection presenting with varying clinical feature from simply to much more severe manifestation. More importantly, widely improper and overuse of antibiotics consumption have caused an endemic of multidrug-resistant-Acinetobacter baumanii leading to prolonged hospital stay and poorer prognosis for intensive care patients. A descriptive study of pre- and post-education was conducted at an intensive care setting in Indonesia. The microbiology data were collected to evaluate the benefit of education on hand hygiene and management of antibiotic use to reduce the number of MDR-Acinetobacter baumanii infection. Based on the result of previous local susceptibility patterns, Cefoperazone/Sulbactam and Amikacin are favored as the empirical therapy. Chi-square analysis shows the significant reduction of Acinetobacter baumanii cases from 70.8% (17/24) to 38% (3/8) with P-value 0.006. Similarly, the susceptibility rate significantly increased, from 21% to 100% to Amikacin; from 5% to 89% to Piperacillin/Tazobactam, and from 42% to 89% to Meropenem. Education improving around hand hygiene, appropriate antibiotic prescribing following local hospital guidelines and the result of antibiotic susceptibility has been shown to reduce the transmission of MDR-Acinetobacter baumanii in the intensive care in our unit within this Indonesian hospital.

Keywords

Acinetobacter baumanii, Hand Hygiene, Antibiotic Prescribing, Intensive Care

Conflicts of Interest

The authors declare no conflicts of interest.

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