The CARSO (Computer Aided Response Surface Optimization) Procedure in Optimization Studies

Mauro Fernandi; Massimo Baroni; Matteo Bazzurri; Paolo Benedetti; Danilo Chiocchini; Diego Decastri; Cynthia Ebert; Lucia Gardossi; Giuseppe Marco Randazzo; Sergio Clementi

doi:10.4236/am.2015.611172

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Applied Mathematics > Vol.6 No.11, October 2015

The CARSO (Computer Aided Response Surface Optimization) Procedure in Optimization Studies ()

Mauro Fernandi¹, Massimo Baroni², Matteo Bazzurri², Paolo Benedetti², Danilo Chiocchini³, Diego Decastri¹, Cynthia Ebert⁴, Lucia Gardossi⁴, Giuseppe Marco Randazzo², Sergio Clementi^3*

¹Flint Group, Cinisello Balsamo, Milano, Italy.
²Biology, Biotechnology and Chemistry Department, Section Chemistry, University of Perugia, Perugia, Italy.
³M.I.A. Multivariate Infometric Analysis Srl, Perugia, Italy.
⁴Department of Chemistry and Pharmaceutical Sciences, University of Trieste, Trieste, Italy.

DOI: 10.4236/am.2015.611172 PDF HTML XML 1,759 Downloads 2,119 Views

Abstract

The paper illustrates innovative ways of using the CARSO (Computer Aided Response Surface Optimization) procedure for response surfaces analyses derived by DCM4 experimental designs in multivariate spaces. Within this method, we show a new feature for optimization studies: the results of comparing their quadratic and linear models for discussing the best way to compute the most reliable predictions of future compounds.

Keywords

CARSO Procedure, Design Strategies, Double Circulating Matrices (DCMs), Optimization

Share and Cite:

Fernandi, M. , Baroni, M. , Bazzurri, M. , Benedetti, P. , Chiocchini, D. , Decastri, D. , Ebert, C. , Gardossi, L. , Randazzo, G. and Clementi, S. (2015) The CARSO (Computer Aided Response Surface Optimization) Procedure in Optimization Studies. Applied Mathematics, 6, 1947-1956. doi: 10.4236/am.2015.611172.

Conflicts of Interest

The authors declare no conflicts of interest.

References

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