Physical Properties of Chitosan Films Obtained after Neutralization of Polycation by Slow Drip Method

Jaiber Humberto Rodriguez Llanos; Luci Cristina de Oliveira Vercik; Andrés Vercik

doi:10.4236/jbnb.2015.64026

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Journal of Biomaterials and Nanobiotechn... > Vol.6 No.4, October 2015

Physical Properties of Chitosan Films Obtained after Neutralization of Polycation by Slow Drip Method ()

Jaiber Humberto Rodriguez Llanos, Luci Cristina de Oliveira Vercik, Andrés Vercik

Basic Sciences Department, Faculty of Animal Science and Food Engineering, University of S?o Paulo, Pirassununga, S?o Paulo, Brazil.

DOI: 10.4236/jbnb.2015.64026 PDF HTML XML 5,552 Downloads 6,382 Views Citations

Abstract

The development of new materials from biodegradable constituents is enticing for applications in bioelectronics and biomedicine, due to their considerable durability, versatility and biodegrada-bility. The present work aims to determine the chemical and physical properties of chitosan membranes after neutralization of the polycation solution. This work was divided into two stages: solubilization and neutralization. In the first stage, the chitosan was solubilized with three different concentrations of acetic acid (1%, 0.8% and 0.5%) in order to evaluate whether the acid affected the physical-chemical properties of the films. In the second stage, the chitosan polycation was neutralized with two strong bases (NaOH and KOH) using three different molar concentrations, by the slow drip method for obtaining films with pH values close to neutrality. The characterization of the membranes obtained from casting method showed that the different concentrations of acetic acid did not affect the physical-chemical properties of the films. In contrast, the neutralization process did affect their properties, and in particular, different behaviors were observed depending on the type of base used for neutralization. More ductile and plasticity were obtained in the films when the polycation was neutralized with KOH, whereas the films neutralized with NaOH exhibited a more fragile behavior.

Keywords

Biodgradavel Film, Chitosan, Hydrogel, Mechanical Properties, Swelling

Share and Cite:

Llanos, J. , Vercik, L. and Vercik, A. (2015) Physical Properties of Chitosan Films Obtained after Neutralization of Polycation by Slow Drip Method. Journal of Biomaterials and Nanobiotechnology, 6, 276-291. doi: 10.4236/jbnb.2015.64026.

Conflicts of Interest

The authors declare no conflicts of interest.

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