Kikuchi-Fujimoto Disease Mimicking Tuberculosis


A 32-year-old woman presented with a fever and cervical lymphadenopathies. The research for Mycobacterium tuberculosis was negative. Tuberculin skin test was positive. Laboratory investigations showed an elevated erythrocyte sedimentation rate and a normal white blood cell count. Bacteriological and viral investigations were negative. Quantiferon-Tb Gold test was indeterminate. Thraco-abdominal and pelvic computed tomography, FDG-PET and gallium scintigraphy revealed no abnormalities. Histological study of cervical lymph node biopsy found signs in favor of histiocytic necrotizing lymphadenitis. There were no epithelioid cell granulomas. A test tuberculosis treatment was refused by the patient. The evolution was marked by spontaneous clinical and biological resolution in fifty days. The negative Lowenstein-Jensen culture eliminated formally the tuberculosis. KFD was thus the most likely diagnosis.

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Mahfoudhi, M. , Gorsane, I. , Turki, S. and Abdallah, T. (2015) Kikuchi-Fujimoto Disease Mimicking Tuberculosis. International Journal of Clinical Medicine, 6, 725-728. doi: 10.4236/ijcm.2015.610096.

Conflicts of Interest

The authors declare no conflicts of interest.


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