Comparison among Cornelian Cherry and Prunus cerasus According to Phenolic Content and Antioxidant Capacity by Three Various Methods of Extraction


Cornelian cherry and Prunus cerasus with red pigments possess precious source of flavonoids and phenolic acids which have various applications in treatment of various health problems. This study is conducted to compare different methods of extraction (shaking incubator, soxhelet, ultrasonic) were applied in order to identify the best method which shows the highest rate of antioxidant capacity by DPPH and ferric reducing antioxidant power (FRAP) methods and total phenolic compounds via Folin-Ciocalteu procedure, p-coumaric acid content of fruits were evaluated by high performance liquid chromatography (HPLC). As a result, cornelian cherry with 1313.13 mg/Kg average TPC score exhibits higher total phenolic content than Prunus cerasus with 1270 mg/Kg. It’s notice worthy that there was a slight difference among antioxidant activity in two fruits. Consequently, DPPH revealed nearly stronger antioxidant activity for Prunus cerasus while cornelian cherry had a little more potent antioxidant activity according to FRAP Test. p-coumaric acid content was almost twice in Prunus cerasus (10.8 mg/ml) than cornelian cherry (5.6 mg/ml). In addition, both shaking incubator and ultrasonic extraction procedures were more efficient than soxhelet in two fruits.

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Behrangi, N. , Ghafoori, H. , Farahmand, Z. , Khani, E. and Sanati, M. (2015) Comparison among Cornelian Cherry and Prunus cerasus According to Phenolic Content and Antioxidant Capacity by Three Various Methods of Extraction. Food and Nutrition Sciences, 6, 1166-1173. doi: 10.4236/fns.2015.612122.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Mamedov, N. and Craker, L. (2002) Cornelian Cherry: A Prospective Source for Phytomedicine. XXVI International Horticultural Congress: The Future for Medicinal and Aromatic Plants.
[2] Reich, L., et al. (1996) Cornelian Cherry from the Shores of Ancient Greece. The Magazine of the Arnold Arboretum, 56, 2-7.
[3] Krosniak, M., et al. (2010) Cornelian Cherry (Cornus mas L.) Juices as a Source of Minerals in Human Diet. Journal of Toxicology and Environmental Health, Part A, 73, 1155-1158.
[4] Hassanpour, H., et al. (2011) Antioxidant Capacity and Phytochemical Properties of Cornelian Cherry (Cornus mas L.) Genotypes in Iran. Scientia Horticulturae, 129, 459-463.
[5] Capanoglu, E., et al. (2011) Procyanidins in Fruit from Sour Cherry (Prunus cerasus) Differ Strongly in Chainlength from Those in Laurel Cherry (Prunus lauracerasus) and Cornelian Cherry (Cornus mas). Journal of Berry Research, 1, 137-146.
[6] Yilmaz, K.U., et al. (2009) Preliminary Characterisation of Cornelian Cherry (Cornusmas L.) Genotypes for Their Physico-Chemical Properties. Food Chemistry, 114, 408-412.
[7] Jayaprakasam, B., et al. (2006) Amelioration of Obesity and Glucose Intolerance in High-Fat-Fed C57BL/6 Mice by Anthocyanins and Ursolic Acid in Cornelian Cherry (Cornus mas). Journal of Agricultural and Food Chemistry, 54, 243-248.
[8] Tural, S. and Koca, I. (2008) Physico-Chemical and Antioxidant Properties of Cornelian Cherry Fruits (Cornus mas L.) Grown in Turkey. Scientia Horticulturae, 116, 362-366.
[9] Schuster, M., et al. (2011) Interspecific Hybridization in Sweet and Sour Cherry Breeding. XIII Eucarpia Symposium on Fruit Breeding and Genetics.
[10] Ferretti, G., et al. (2010) Cherry Antioxidants: From Farm to Table. Molecules, 15, 6993-7005.
[11] Mulabagal, V., Lang, G.A., DeWitt, D.L., Dalavoy, S.S. and Nair, M.G. (2009) Anthocyanin Content, Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Activities of Sweet and Sour Cherries. Journal of Agricultural and Food Chemistry, 57, 1239-1246.
[12] Wang, H.B., Nair, M.G., Strasburg, G.M., Booren, A.M. and Gray, J.I. (1999) Novel Antioxidant Compounds from Tart Cherries (Prunus cerasus). Journal of Natural Products, 62, 86-88.
[13] Ataie-Jafari, A., Hosseini, S., Karimi, F. and Pajouhi, M. (2008) Effects of Sour Cherry Juice on Blood Glucose and Some Cardiovascular Risk Factors Improvements in Diabetic Women: A Pilot Study. Nutrition & Food Science, 38, 355-360.
[14] Saric, A., Sobocanec, S., Balog, T., Kusic, B., Sverko, V., Dragovic-Uzelac, V., et al. (2009) Improved Antioxidant and Anti-Inflammatory Potential in Mice Consuming Sour Cherry Juice (Prunus cerasus cv. Maraska). Plant Foods for Human Nutrition, 64, 231-237.
[15] Tall, J.M. and Raja, S.N. (2004) Dietary Constituents as Novel Therapies for Pain. The Clinical Journal of Pain, 20, 19-26.
[16] Traustadóttir, T., Davies, S.S., Stock, A.A., Su, Y.L., Heward, C.B., Roberts II, L.J. and Harman, S.M. (2009) Tart Cherry Juice Decreases Oxidative Stress in Healthy Older Men and Women. The Journal of Nutrition, 139, 1896-1900.
[17] Kuehl, K.S., Perrier, E.T., Elliot, D.L. and Chesnutt, J.C. (2010) Research Article Efficacy of Tart Cherry Juice in Reducing Muscle Pain during Running: A Randomized Controlled Trial. Journal of the International Society of Sports Nutrition, 7, 17.
[18] Connolly, D., McHugh, M. and Padilla-Zakour, O. (2006) Efficacy of a Tart Cherry Juice Blend in Preventing the Symptoms of Muscle Damage. British Journal of Sports Medicine, 40, 679-683.
[19] Gunduz, K., Saracoglu, O., Özgen, M. and Serce, S. (2013) Antioxidant, Physical and Chemical Characteristics of Cornelian Cherry Fruits (Cornus mas L.) at Different Stages of Ripeness. Acta Scientiarum Polonorum-Hortorum Cultus, 12, 59-66.
[20] Ferretti, G., Neri, D. and Bacchetti, T. (2014) Effect of Italian Sour Cherry (Prunus cerasus L.) on the Formation of Advanced Glycation End Products and Lipid Peroxidation. Food and Nutrition Sciences, 5, 1568-1576.
[21] Kim, D.-O., Heo, H.J., Kim, Y.J., Yang, H.S. and Lee, C.Y. (2005) Sweet and Sour Cherry Phenolics and Their Protective Effects on Neuronal Cells. Journal of Agricultural and Food Chemistry, 53, 9921-9927.
[22] Rop, O., Mlcek, J., Kramarova, D. and Jurikova, T. (2010) Selected Cultivars of Cornelian Cherry (Cornus mas L.) as a New Food Source for Human Nutrition. African Journal of Biotechnology, 9, 1205-1210.
[23] Melichácová, S., Timoracká, M., Bystrická, J., Vollmannová, A. and Céry, J. (2010) Relation of Total Antiradical Activity and Total Polyphenol Content of Sweet Cherries (Prunus avium L.) and Tart Cherries (Prunus cerasus L.). Acta Agriculturae Slovenica, 95, 21-28.
[24] Badalica-Petrescu, M., Dragan, S., Ranga, F., Fetea, F. and Socaciu, C. (2014) Comparative HPLC-DAD-ESI (+) MS Fingerprint and Quantification of Phenolic and Flavonoid Composition of Aqueous Leaf Extracts of Cornus mas and Crataegus monogyna, in Relation to Their Cardiotonic Potential. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 42, 9-18.
[25] Simonian, S. (2000) Anthocyanin and Antioxidant Analysis of Sweet and Tart Cherry Varieties of the Pacific Northwest.

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