Noninvasive Assessment of Liver Disease—Measurement of Hepatic Fibrosis Using Shear Wave Elastography (SWE)

Naoki Hotta

Department of Internal Medicine, Division of Gastroenterology, Masuko Momorial Hospital, Nagoya, Japan.

DOI: 10.4236/ojmi.2015.53014                

Abstract

The evaluation of liver fibrosis is said to be one of the factors of the liver cancer development. The noninvasive testing is considered for abdominal echography, MRI, a blood marker in various ways. We announce the evaluation as an article by liver fibrosis using the probe for the heart before, too. This time is shear wave elastography using the echo probe for the abdomen (SWE). We used and examined it in normal, chronic hepatitis patients with cirrhosis. We tried it, but, in the patients with cirrhosis, there was no examination in the change in a value after ascites time and ascitic drainage. The future examination thinks about a comparison with the liver biopsy, the comparison with the liver fibrosis marker. Also, we think that a malignancy and the benign differentiation should be possible for a liver tumor.

Keywords

Shear Wave Elastography (SWE), Hepatic Fibrosis

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Kawamoto, M., Mizuguchi, T., Katsuramaki, T., et al. (2006) Assessment of Liver Fibrosis by a Noninvasive Method of Transient Elastography and Biochemical Markers. World Journal of Gastroenterology, 12, 4325-4330.
[2]	Kazemi, F., Kettaneh, A., Nkontchou, G., et al. (2006) Liver Stiffness Measurement Selects Patients with Cirrhosis at Risk of Bearing Large Oesophageal Varices. Journal of Hepatology, 45, 230-235. http://dx.doi.org/10.1016/j.jhep.2006.04.006
[3]	Castera, L., Vergniol, J., Foucher, J., et al. (2005) Prospective Comparison of Transient Elastography, Fibrotest, APRI and Liver Biopsy for the Assessment of Fibrosis in Chronic Hepatitis C. Gastroenterology, 128, 343-350. http://dx.doi.org/10.1053/j.gastro.2004.11.018
[4]	Ziol, M., Handra-Luca, A., Kettaneh, A., et al. (2005) Noninvasive Assessment of Liver Fibrosis by Measurement of Stiffness in Patients with Chronic Hepatitis C. Hepatology, 41, 48-54. http://dx.doi.org/10.1002/hep.20506
[5]	Foucher, J., Chanteloup, E., Vergniol, J., et al. (2006) Diagnosis of Cirrhosis by Transient Elastography (FibroScan): A Prospective Study. Gut, 55, 403-408. http://dx.doi.org/10.1136/gut.2005.069153
[6]	Colletta, C., Smirne, C., Fabris, C., et al. (2005) Value of Two Noninvasive Methods to Detect Progression of Fibrosis among HCV Carriers with Normal Aminotransferases. Hepatology, 42, 838-845. http://dx.doi.org/10.1002/hep.20814
[7]	Morishima, C., Morgan, T.R., Everhart, J.E., et al. (2006) HCV RNA Detection by TMA during the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (Halt-C) Trial. Hepatology, 44, 360-367. http://dx.doi.org/10.1002/hep.21265
[8]	Fontana, R.J., Sanyal, A.J., Mehta, S., et al. (2006) Portal Hypertensive Gastropathy in Chronic Hepatitis C Patients with Bridging Fibrosis and Compensated Cirrhosis: Results from the HALT-C Trial. American Journal of Gastroenterology, 101, 983-992. http://dx.doi.org/10.1111/j.1572-0241.2006.00461.x
[9]	Giovanna, F., Carlo, F., Laurent, C., et al. (2015) WFUMB Guidelines and Recommendations for Clinical Use of Ultrasound Elastgraphy: Part 3: LIVER. Ultrasound in Medicine and Biology, 41, 1161-1179. http://dx.doi.org/10.1016/j.ultrasmedbio.2015.03.007
[10]	Yamasaki, K., Tatoyama, M., Abirn, S., et al. (2014) Elevated Serum Levels of Wisteria Floribunda Agglutinin-Posi- tive Human Mac-2 Binding Protein Predict the Development of Hepatocellular Carcinoma in Hepatitis C Patients. Hepatology, 60, 1563-1573. http://dx.doi.org/10.1002/hep.27305
[11]	Kang, J., Kwon, H., Cho, J., et al. (2012) Comparative Study of Shear Wave Velocities Using Acoustic Radiation Force Impulse Technology in Hepatocellular Carcinoma: The Extent of Radiofrequency Ablation. Gut and Liver, 6, 362-367. http://dx.doi.org/10.5009/gnl.2012.6.3.362
[12]	Xu, X., Luo, L., Chen, J., et al. (2014) Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound. BioMed Research International, 2014, Article ID 901642, 7 p.