Management of Cervical Intra Epithelial Neoplasia by Loop Electrosurgical Excision Procedure in a Low Resource Country: An Experience from the Yaoundé General Hospital, Cameroon

Jean Dupont Kemfang Ngowa; Anny Ngassam; Jovanny Fouogue Tsuala; Juny Metogo; Zacharie Sando; Angèle Kabeyene; Jean Marie Kasia

doi:10.4236/ojog.2015.59070

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OJOG> Vol.5 No.9, August 2015

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Management of Cervical Intra Epithelial Neoplasia by Loop Electrosurgical Excision Procedure in a Low Resource Country: An Experience from the Yaoundé General Hospital, Cameroon

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DOI: 10.4236/ojog.2015.59070 2,380 Downloads 2,769 Views Citations

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Jean Dupont Kemfang Ngowa^1,2*, Anny Ngassam², Jovanny Fouogue Tsuala², Juny Metogo², Zacharie Sando³, Angèle Kabeyene³, Jean Marie Kasia^1,2

Affiliation(s)

¹Obstetrics and Gynecology Unit, Yaoundé General Hospital, Yaoundé, Cameroon.
²Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
³Department of Pathology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.

ABSTRACT

Background: Cervical cancer is the third most common cancer worldwide, and 80% of cases occur in the developing world. A critical component of effective cervical cancer screening programs is the ability to offer women appropriate and effective treatment for cervical intra epithelial neoplasia (CIN). Objectives: This study aimed at assessing the primary experience of management of CIN by Loop Electrosurgical Excision Procedure (LEEP) in a low resource country. Methods: We carried out a descriptive cross sectional study at the Yaoundé General Hospital in Cameroon. Results: Twenty three cases of CIN were treated by LEEP. Mean age of patients was 40.5 ± 9.9 years. Six (26.1%) patients were infected by the Human Immunodeficiency Virus (HIV). LEEP was indicated in 21 (91.30%) cases for CIN2 and CIN3. The mean duration of the surgical procedure was 10 ± 3 minutes. There was one (4.3%) complication (persistent cervical bleeding). Surgical margins were negative for dysplasia or invasive carcinoma in 18 (78.26%) cases and non-applicable in 5 (21.73%) cases (thermal artefacts of margins and cervicitis without CIN). One patient with micro invasive carcinoma on post-operative histology was treated by total hysterectomy. Cervical cytology was normal at 6 months post LEEP for 15 cases out of 16 (93.8%) patients who performed the test. One woman achieved pregnancy and delivered a term baby. Conclusion: Treatment of CIN by LEEP is feasible, safe and effective in our setting.

KEYWORDS

Cervical Cancer, Cervical Intraepithelial Neoplasia, LEEP, Screening Cervical Cancer, Low Resource Country

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Ngowa, J. , Ngassam, A. , Tsuala, J. , Metogo, J. , Sando, Z. , Kabeyene, A. and Kasia, J. (2015) Management of Cervical Intra Epithelial Neoplasia by Loop Electrosurgical Excision Procedure in a Low Resource Country: An Experience from the Yaoundé General Hospital, Cameroon. Open Journal of Obstetrics and Gynecology, 5, 481-486. doi: 10.4236/ojog.2015.59070.

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