Resistant Tremors and Unexplained Weight Loss Could Also Be a Sign of HIV

DOI: 10.4236/nm.2015.63014   PDF   HTML   XML   3,860 Downloads   4,269 Views  

Abstract

This case study is done to show a different type of presentation of a HIV (Human Immunodeficiency Virus) patient. Neurological symptoms in HIV are normally due to Progressive Multifocal Leukoencephalopathy (PML) which is a reactivated infection caused by John Cunningham virus (JC virus). The disease causes fatal demyelination of the central nervous system (CNS). This case presented a 51-year-old Nigerian man who complained of resistant tremors and unexplained weight loss. The patient was suspected to have HIV when a MRI scan revealed T2/FLAIR hyper intensity of white matter which was a sign of PML. HIV ELISA was done and came back with a positive result. PML presenting in the form of tremors is very rare and more research is required to focus on the neurological presentation of HIV.

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Hamdy Ibrahim, M. , Kumar, S. , Sirsat, J. , Khalid, M. and Kumar, K. (2015) Resistant Tremors and Unexplained Weight Loss Could Also Be a Sign of HIV. Neuroscience and Medicine, 6, 81-83. doi: 10.4236/nm.2015.63014.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] http://www.who.int/hiv/pub/guidelines/HIVstaging150307.pdf
[2] http://www.who.int/topics/hiv_aids/en/
[3] Koralnik, I.J. (2004) New Insights into Progressive Multifocal Leukoencephalopathy. Current Opinion in Neurology, 17, 365-370.
http://dx.doi.org/10.1097/00019052-200406000-00019
[4] Nived, O., Bengtsson, A.A., Jönsen, A. and Sturfelt, G. (2008) Progressive Multifocal Leukoencephalopathy—The Importance of Early Diagnosis Illustrated in Four Cases. Lupus, 17, 1036-41.
[5] Berger, J.R. and Koralnik, I.J. (2005) Progressive Multifocal Leukoencephalopathy and the Use of Natalizumab— Unforeseen Consequences. The New England Journal of Medicine, 353, 414-416.
http://dx.doi.org/10.1056/NEJMe058122
[6] Sakai, M., Inoue, Y., Aoki, S., Sirasaka, T., Uehira, T., Takahama, S., et al. (2009) Follow-Up Magnetic Resonance Imaging Findings in Patients with Progressive Multifocal Leukoencephalopathy: Evaluation of Long-Term Survivors under Highly Active Antiretroviral Therapy. Japanese Journal of Radiology, 27, 69-77.
[7] Cardoso, F. (2002) HIV-Related Movement Disorders. CNS Drugs, 16, 663-668.
http://dx.doi.org/10.2165/00023210-200216100-00002
[8] Sporer, B., Seelos, K., Asmus, F., Boetzel, K. and Pfister, H.-W. (2005) Posterior Fossa Tremor Induced by HIV-Associated Progressive Multifocal Leukoencephalopathy. European Neurology, 53, 96-97.
http://dx.doi.org/10.1159/000085507
[9] Tse, W., Cersosimo, M.G., Gracies, J.M., Morgello, S., Olanow, C.W. and Koller, W. (2004) Movement Disorders and AIDS: A Review. Parkinsonism & Related Disorders, 10, 323-324.
http://dx.doi.org/10.1016/j.parkreldis.2004.03.001

  
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