The Application of Molecularly Imprinted Polymers

Ming Zhao, Guijun Shen^*

College of Environmental and Chemical Engineering, Dalian University, Dalian, China.

DOI: 10.4236/msce.2015.37010                

Abstract

Molecularly imprinted technology (MIT) has the characteristics of specificity and high selectivity, which is one of the most promising methodologies. Besides, the polymers are made using MIT as the functional material of solid-phase extraction and chromatographic fractionating and sensor, because of the characteristics of the high selectivity, the better stability and easy preparation. This review introduces the progress in the application of MIT and summarizes its application in the chemistry.

Keywords

Molecularly Imprinted Polymers, Solid Phase Extraction, Chromatographic Fractionating

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Feng, Y.Q., Zhou, R.J., Tang, Y.B. and Hu, X.X. (2011) The Application of Molecularly Imprinted in Solid Phase Extraction. PTCA (PARTB: CHEM, ANAL), 47, 125-128.
[2]	Yan, H.Y., Wang, F. and Han, D.D. (2012) Simultaneous Determination of Four Plant Hormones in Bananas by Molecularly Imprinted Solid-Phase Extraction Coupled with High Performance Liquid Chromatography. ANALYST, 137, 2884-2890. http://dx.doi.org/10.1039/c2an35362h
[3]	Djozan, D. and Ebrahimi, B. (2008) Preparation of New Solid Phase Micro Extraction Fiber on the Basis of Atrazine- Molecular Imprinted Polymer: Application for GC and GC/MS Screening of Triazine Herbicides in Water, Rice and Onion. Analytical Chemical Acta, 616, 152-159. http://dx.doi.org/10.1016/j.aca.2008.04.037
[4]	Caro, E., Marcel, R.M., Cormack, P.A.G., Sherrington, D.C. and Borrull, F. (2003) On-Line Solid-Phase Extraction with Molecularly Imprinted Polymers to Selectively Extract Substituted 4-Chlorophenols and 4-Nitrophenol from Water. Chromatogram A, 995, 233-238. http://dx.doi.org/10.1016/S0021-9673(03)00543-0
[5]	Wulff, G. (1995) Molecular Imprinting in Cross-Linking Materials with the Aid of Molecular Templates a Way towards Artificial Antibodies. Angewandte Chemie International Edition, 34, 1812-1832. http://dx.doi.org/10.1002/anie.199518121
[6]	Wei, Y.F., Fan, J. and Shao, X.J. (2008) Preparation of Diphenylguani-dine-Imprinted Polymer and Its Application for Solid-Phase Extraction. Journal of Instrumental Analysis, 10, 1039-1043.
[7]	Hu, Y.F., Zhang, Z.H., Zhang, H.B., Luo, L.J. and Yao, S.Z. (2012) Selective and Sensitive Molecularly Im-printed Sol- Gel Film-Based Electrochemical Sensor Combining Mercaptoacetic Acid-Modified PbS Nanoparticles with Fe3O4@Au- Multi-Walled Carbon Nanotubes-Chitosan. Journal of Solid State Electrochemistry, 16, 857-867. http://dx.doi.org/10.1007/s10008-011-1434-4
[8]	Yng, M.L., Shen, R.L., Gu, W.C., Chu, X.G. and Wang, D.N. (2012) Study on Methyltestosterone Imprinted Polymers and Its Application in Solid Phase Extraction. Chinese Journal of Veterinary Drug, 12, 6-8.
[9]	Wng, Y., Xu, X.W. and Ling, S. (2010) Synthesis of Dimethomorph Imprinted Polymers and Molecularly Imprinted Solid-Phase Extraction Analysis. Guangdong Journal of Chemistry, 37, 7.
[10]	Shi, Y., Peng, D.D., Shi, C.H., Zhang, X. and Xie, Y.T. (2011) Selective Determination of Trace 17β-Estradiol in Dairy and Meat Samples by Molecularly Imprinted Solid-Phase Extraction and HPLC. Food Chemistry, 126, 1916- 1925. http://dx.doi.org/10.1016/j.foodchem.2010.12.020
[11]	Huang, Y., Zhang, Q.J. and Liu, M. (2012) Molecularly-Imprinted Solid Phase Extraction Coupled with High Performance Liquid Chromatography for the Determination of Ractopamine in Feed Samples. Chinese Journal of Chromatography, 1, 56-61.
[12]	Hu, J., Wu, X.Y. and Gao, W.H. (2012) HPLC Analysis of Two Triazole Fungicide Residues by Molecularly Imprinted Solid Phase Extraction. Chinese Journal of Pharmaceutical Analysis, 32, 6.
[13]	Li, Z.W., Liu, S.B. and Yang, G.L. (2005) Fast Seperation of Nicotinamide and Nicotinic Acid with Molecularly Imprinted Monolithic Column. Chinese Journal of Chromatography, 6, 622-655.
[14]	Liu, C., Muhammad, T., Piletska, E.V. and Zeng, H.-H. (2010) Synthesis of Lidocaine Molecularly Imprinted Polymers and Application on Solid Phase Extraction. Chinese Journal of Analytical Chemistry, 11, 1652-1656.