Experience of Percutaneus Kidney Biopsy from a Tertiary Care Center of Pakistan

Abstract Full-Text HTML XML Download Download as PDF (Size:224KB) PP. 61-66
DOI: 10.4236/ojneph.2015.52010    3,390 Downloads   4,066 Views   Citations

ABSTRACT

Background: Kidney biopsy is one of the most important tools in the assessment of kidney disease. Knowing the histopathology is important for immediate clinical management. It helps in predicting the long term prognosis and in planning for prevention of chronic kidney disease. Methods: This is a cross section study of percutaneus biopsies of the native kidneys of patients, who presented to the Aga Khan University Hospital Karachi Pakistan, over ten year period from 2003 to 2012. Age range was 16 to 77 years. Results: Total number of 435 biopsies were included in the study. The most common histopathological findings, regardless of the indication of biopsy were Tubulo Interstitial Nephritis in 15 percent, followed by Membranous Nephropathy in 12 percent, Focal Segmental Glomerulosclerosis in 8 percent and Membrano Proliferative Glomerulonephritis also in 8 percent. Conclusion: This study will help in better understanding the spectrum of renal disease in Pakistan. It will guide the clinician in the management and provide a data base or a starting point for the researchers for conducting the controlled and population base studies.

Cite this paper

Absar, A. , Asif, N. , Khan, Q. and Kashif, W. (2015) Experience of Percutaneus Kidney Biopsy from a Tertiary Care Center of Pakistan. Open Journal of Nephrology, 5, 61-66. doi: 10.4236/ojneph.2015.52010.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Taal, M.W., et al. (2011) The Renal Biopsy. In: Brenner & Rector’s The Kidney, 9th Edition, Saunders Elsevier, Philadelphia.
http://www.clinicalkey.com
[2] Johnson, R.J., et al. (2015) Renal Biopsy. In: Comprehensive Clinical Nephrology, 5th Edition, Saunders Elsevier, Philadelphia.
[3] Jafar, T.H. (2006) The Growing Burden of Chronic Kidney Disease in Pakistan. The New England Journal of Medicine, 354, 995-997.
http://dx.doi.org/10.1056/NEJMp058319
[4] Rychlik, I., Jancova, E., Tesar, V., Kolskey, A., Lacha, J., Stegskal, J., et al. (2004) The Czech Registry of Renal Biopsy. Nephrology Dialysis Transplantation, 19, 3040-3049.
http://dx.doi.org/10.1093/ndt/gfh521
[5] Choi, I.J., Jeong, H.J., Han, D.S., Lee, J.S., Choi, K.H., Kang, S.W., et al. (2001) Analysis of 4515 Cases of Renal Biopsy in Korea. Yonseri Medical Journal, 42, 247-254.
http://dx.doi.org/10.3349/ymj.2001.42.2.247
[6] Gesualdo, L., Di Palma, A.M., Morrone, L.F., Strippoli, G.F. and Schena, F.P. (2004) The Italian Experience of the National Registry of Renal Biopsy. Kidney International, 66, 890-894.
http://dx.doi.org/10.1111/j.1523-1755.2004.00831.x
[7] Covic, A., Schiller, A., Carmen, V., Gluhovschi, G., et al. (2006) Epidemiology of Renal Disease in Romania. Nephrology Dialysis Transplantation, 21, 419-424.
http://dx.doi.org/10.1093/ndt/gfi207
[8] Rivera, F., Lopez-Gomez, J. and Perez Garcia, R. (2004) Clinicopathological Correlation of Renal Pathology in Spain. Kidney International, 66, 898-904.
http://dx.doi.org/10.1111/j.1523-1755.2004.00833.x
[9] Yahya, T.M., Pingle, A., Boobes, Y. and Pingle, S. (1998) Analysis of 490 Kidney Biopsies: Data from United Arab Emirates Renal Disease Registry. Journal of Nephrology, 11, 148-150.
[10] Narasimhan, B., Chacho, B., John, G.T., Korula, A., Kirubakaran, M.G. and Jacob, C.K. (2006) Characterization of Kidney Lesions in Indian Adalts: Towards a Renal Biopsy Registry. Journal of Nephrology, 19, 205-210.
[11] Prakash, J., Singh, A.K. and Sexana, R.K. (2003) Glomerular Diseases in the Elderly in India. International Urology and Nephrology, 35, 283-288.
http://dx.doi.org/10.1023/B:UROL.0000020429.14190.5b
[12] Swaminathan, S., Leung, N., Lager, D.J., Melton, L.J., Bergstralh, E.J., Rohlinger, A. and Fervenza, F.C. (2006) Changing Incidence of Glomerular Disease in Olmsted County, Minnesota: A 30-Year Renal Biopsy Study. Clinical Journal of the American Society of Nephrology, 1, 483-487.
http://dx.doi.org/10.2215/CJN.00710805
[13] Haas, M., Meehan, S.M., Karrison, T.G. and Spargo, B.H. (1997) Changing Etiologies of Unexplained Adult Nephrotic Syndrome: A Comparison of Renal Biopsy Findings from 1976-1979 and 1995-1997. American Journal of Kidney Diseases, 30, 621-631.
http://dx.doi.org/10.1016/S0272-6386(97)90485-6
[14] Dragovic, D., Rosenstock, J.L., Wahl, S.J., Panagopoulos, G., Devita, M.V. and Michelis, M.F. (2005) Increasing Incidence of Focal Segmental Glomerulosclerosis and an Examination of Demographic Patterns. Clinical Nephrology, 63, 1-7.
http://dx.doi.org/10.5414/CNP63001
[15] Jamal, Q., Jafarey, N.A. and Navi, A.J. (1988) A Review of 1508 Percutaneous Renal Biopsies. Journal of Pakistan Medical Association, 38, 272-275.
[16] Muzaffar, M., Mushtaq, S., Khadim, M.T., Nabiruddin and Mamoon, N. (1997) Morphological Pattern of Glomerular Diseases in Patients with Nephrotic Syndrome in Northern Pakistan. Pakistan Armed Forces Medical Journal, 47, 3-6.
[17] Osmani, M.H. and Frooqi, S. (2001) An Audit of Renal Biopsies. Journal of Surgery Pakistan, 6, 28-30.
[18] Khan, A.Z., Anwar, N., Munib, M. and Shah, F. (2004) Histological Pattern of Glomerulopathies at Khyber Teaching Hospital, Peshawar. Pakistan Journal of Medical Research, 43, 117-120.
[19] Kazi, J.I. and Mubarak, M. (2007) Pattern of Glomerulonephritides in Adult Nephritic Patients Report from SIUT (Letter to the Editor). Journal of Pakistan Medical Association, 57, 574.
[20] Zaffar, S.A. and Ali, A. (2008) Histological Pattern of Nephrotic Syndrome in Elderly Patients. Journal of Ayub Medical College Abbottabad, 20, 97-99.
[21] Mubarak, M., Kazi, J.I., Naqvi, R., Ahmed, E., Akhter, F., Naqvi, S.A. and Rizvi, S.A. (2011) Pattern of Renal Diseases Observed in Native Renal Biopsies in Adults in a Single Centre in Pakistan. Nephrology, 16, 87-92.
http://dx.doi.org/10.1111/j.1440-1797.2010.01410.x
[22] Abbas, K., Mubarak, M., Kaziet, J.I. and Muzaffar, R. (2009) Pattern of Morphology in Renal Biopsies of Nephritic Syndrome Patients. Correlation with Immunoglobulin and Complement Deposition and Serology. Journal of Pakistan Medical Association, 59, 540-543.
[23] Sabir, S., Mubarak, M., Ul-Haq, I. and Bibi, A. (2013) Pattern of Biopsy Proven Renal Disease at PNS SHIFA Karachi: A Cross-Sectional Survey. Journal of Renal Injury Prevention, 2, 133-137.
[24] Choudhary, M., Masood, A., Rashid, F., Mand, A. and Nagi, A.H. (2014) Morphological Pattern of Glomerulonephritis in Males: A Multicenter Study. Biomedica, 30, 110-114.

  
comments powered by Disqus

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.