Antimicrobial Susceptibility of Multidrug-Resistant Acinetobacter baumanii in a Teaching Hospital: A Two-Year Observation

Cucunawangsih  ¹, Veronica Wiwing¹, Nata Pratama Hardjo Lugito²

¹Department of Microbiology, Faculty of Medicine, University of PelitaHarapan, Tangerang, Indonesia.
²Department of Internal Medicine, Faculty of Medicine, University of PelitaHarapan, Tangerang, Indonesia.

DOI: 10.4236/ojmm.2015.52010                

Abstract

Multidrug-resistant (MDR) Acinetobacter baumanii (A. baumanii) caused hospital acquired infection, typically in critical-ill patients with medical devices. This is a retrospective descriptive study on epidemiology and microbiology data to determine the antimicrobial susceptibility pattern of MDR-Acinetobacter baumanii isolates from a teaching hospital in Tangerang, Indonesia from Januari 2013 to December 2014. A total of 84 A. baumanii were collected. Patients suffering from respiratory tract infection had the highest number (41.7%) of A. baumanii isolate. There were 39 (46.6%) patients admitted in critical care. A. baumanii isolates in this study mostly were multidrug-resistant organisms with low susceptibility level to 11 antibiotic tested, 44% - 69% in 2013 and 26% - 67% in 2014. A high susceptibility level was observed to amikacin (80% and 79% in 2013, 2014 consecutively) and trimethoprim-sulfamethoxazole (73% and 72% in 2013, 2014 consecutively). A. baumanii is a hospital acquired pathogen in critically-ill patients. The susceptibility pattern of this study result showed MDR organism. There was a sharp decrease of susceptibility in all antibiotics studied from 2013 to 2014 except amikacin and trimethoprim-sulfamethoxazole.

Keywords

Multidrug-Resistant Acinetobacter baumanii, Antimicrobial Susceptibility, Amikacin

Conflicts of Interest

The authors declare no conflicts of interest.

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