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A Facile and Inexpensive Synthesis of 6-Ethynylbipyridine

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DOI: 10.4236/ijoc.2011.12006    5,730 Downloads   11,521 Views  

ABSTRACT

An inexpensive synthesis of 6-ethynylbipyridine has been accomplished using Sonogashira coupling of 2-bromo-6-iodopyridine with 2-methyl-3-butyn-2-ol. Subsequent Stille coupling with 2-(trimethylstannanyl) pyridine and hydrolysis provided the target compound in an overall high yield.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

J. Huo and J. Hoberg, "A Facile and Inexpensive Synthesis of 6-Ethynylbipyridine," International Journal of Organic Chemistry, Vol. 1 No. 2, 2011, pp. 33-36. doi: 10.4236/ijoc.2011.12006.

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