Effect of Pressurized Soy Protein Isolate upon the Growth and Antioxidants Functions of SD Rat

Nancy Ali¹, Li Zhang¹, Lili Li¹, Laurie H. M. Chan², Baixiang Li^1*

¹Department of Toxicology, College of Public Health, Harbin Medical University, Harbin, China.
²Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Canada.

DOI: 10.4236/fns.2015.65052                

Abstract

The objective of this study is to specify the effect of pressurized soy protein isolate (pSPI), upon the physical development, growth hormones and antioxidants functions of SD rats. The methodology depends on the selection of one hundred male SD rats, divided randomly into 5 groups. Each group consists of 20 rats. The groups will be defined as one blank control group, three groups with pSPI at low, medium and high doses and another control group with native soy protein isolates (nSPI). Low, medium and high doses are represented by 0.333 g/kg, 1.667 g/kg and 3.333 g/kg pSPI per weight, respectively. The native soy protein isolate is represented by 3.333 g/kg nSPI per weight. In every group, four animals will be taken out to collect the blood samples and analyze insulin like growth factor-I, growth hormone, thyroid stimulating hormone, thyroxine and triiodothyronin. The other SD rats will be subjected to feeding for 63 consecutive days. The body weight, the body length and food intake of each rat are measured. The total antioxidant capacity, superoxide dismutase (SOD), malondialdehyde and Glutathione Peroxidase in liver and serum of each rat will be analyzed. The results indicated that the groups with medium and high dose of pSPI result in an obvious increase in the body weight, body length and food utilization rate of SD rats. Also, pSPI has a great effect on the growth and antioxidants functions of SD rat.

Keywords

Pressurized Soy Protein Isolate, Triiodothyronin, Malondialdehyde, Antioxidants

Conflicts of Interest

The authors declare no conflicts of interest.

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