Rheumatoid Arthritis of Man: A Study of 35 Cases in a Senegalese Hospital

Abstract

Background: Rheumatoid arthritis is predominant in women. In men certain clinical signs can delay diagnosis. Methods: A cross-section study of the epidemio-clinical and immunobiological features of rheumatoid arthritis in a male, black African population was carried out at the Aristide Le Dantec, University hospital of Dakar. Results: we studied 35 male subjects with rheumatoid arthritis. Their mean age was 42 years and the average time between the onset of symptoms to diagnosis was 44 months. In 70% of these patients, at least one joint deformation was present, most frequently an ulnar deviation of the fingers (34.3%). Extra-articular symptoms were dominated by dry eye syndrome (34%) and anemia (17%). Anemia was significantly less frequent in men than in women. The erythrocyte sedimentation rate was accelerated in 51.4% and C reactive proteins were increased in 92% of patients. The rheumatoid factor was positive in all patients and the anticyclic Citrullinated Peptide (CCP) antibody was positive in 80% of cases. Conclusion: Male rheumatoid arthritis, relatively less studied, was associated with strongly positive immunological markers and a high rate of joint disorders.

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Ndongo, S. , Pouye, A. , Ouedraogo, L. , Azankpan, E. , Diack, N. and Diop, T. (2014) Rheumatoid Arthritis of Man: A Study of 35 Cases in a Senegalese Hospital. Open Journal of Internal Medicine, 4, 137-142. doi: 10.4236/ojim.2014.44021.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Morel, J., Miossec, P. and Combe, B. (2004) Immunopathologie de la polyarthrite rhumatoide. EMC Rhumatologie Orthopédie, 1, 218-230.
http://dx.doi.org/10.1016/j.emcrho.2004.03.003
[2] Sokka, T., Abelson, B. and Pincus, T. (2008) Mortality in Rheumatoid Arthritis: 2008 Update. Clinical and Experimental Rheumatology, 26, S35-S61.
[3] Guillemin, F., Saraux, A., Guggenbuhl, P., Roux, C.H., Fardellone, P. and Le Bihan, E. (2005) Prevalence of Rheumatoid Arthritis in France: 2001. Annals of the Rheumatic Diseases, 64, 1427-1430.
http://dx.doi.org/10.1136/ard.2004.029199
[4] Kahn, M.F. (2004) Peuton estimer l’incidence et la prévalence de la polyarthrite rhumatoide en France ainsi que leur évolution? Revue du Rhumatisme, 71, 180-182.
http://dx.doi.org/10.1016/j.rhum.2003.10.003
[5] Arnett, F.C., Edworthy, S.M., Bloch, D.A., McShane, D.J., Fries, J.F., Cooper, N.S., et al. (1988) The American Rheumatism Association 1987 Revised Criteria for the Classification of Rheumatoid Arthritis. Arthritis & Rheumatology, 31, 315-324.
http://dx.doi.org/10.1002/art.1780310302
[6] Roux, H. (2002) Polyarthrite rhumatoide en Afrique subsaharienne. Revue du Rhumatisme, 69, 797-800.
http://dx.doi.org/10.1016/S1169-8330(02)00387-3
[7] Widdifield, J., Paterson, J.M., Bernatsky, S., Tu, K., Tomlinson, G., Kuriya, B., et al. (2014) The Epidemiology of Rheumatoid Arthritis in Ontario, Canada. Arthritis & Rheumatology, 66, 786-793.
http://dx.doi.org/10.1002/art.38306
[8] Soubrier, M., Mathieu, S., Payet, S., Dubost, J.-J. and Ristori, J.-M. (2010) La polyarthrite rhumatoide du sujet agé. Revue du Rhumatisme, 77, 326-332.
http://dx.doi.org/10.1016/j.rhum.2009.11.024
[9] Rkain, H., Allali, F., Jroundi, I. and Najia, H.-H. (2006) Retentissement socioéconomique de la polyarthrite rhumatoide (PR) au Maroc. Revue du Rhumatisme, 73, 462-468.
http://dx.doi.org/10.1016/j.rhum.2005.10.011
[10] Frikha, F., Elloumi, H., Marzouk, S., Kaddour, N., Jallouli, M., Kechaou, M., et al. (2007) Polyarthrite rhumatoide masculine: A propos de 46 cas. Revue du Rhumatisme, 74, 1048 p.
http://dx.doi.org/10.1016/j.rhum.2007.10.025
[11] Pillon, F. and Michiels, Y. (2013) Epidémiologie et physiopathologie de la polyarthrite rhumatoide. Actualités Pharmaceutiques, 52, 1-2.
http://dx.doi.org/10.1016/j.actpha.2013.09.018
[12] Slimani, S., Abbas, A., Ammar, A.B., Kebaili, D., Ali, E.H., Rahal, F., et al. (2014) Characteristics of Rheumatoid Arthritis in Algeria: A Multicenter Study. Rheumatology International, 34, 1235-1239.
http://dx.doi.org/10.1007/s00296-014-2981-7
[13] Muis Pistor, O., Fantino, B., Piot-Fantino, F., Garret, C., Trape, G. and Tebiba, J. (2013) Diagnostic et prise en charge thérapeutique de la polyarthrite rhumatoide en Rhône-Alpes: Une enquête “vraie vie” en 2010. Revue du Rhumatisme, 80, 130-135.
http://dx.doi.org/10.1016/j.rhum.2012.04.011
[14] Chammas, M. (2005) Le poignet rhumatoide. Chirurgie de la Main, 245, 275-298.
http://dx.doi.org/10.1016/j.main.2005.10.001
[15] Macholds, K.P., Stamm, T.A., Eberl, G.J., Nell, V.K., Dunky, A., Uffmann, M., et al. (2002) Very Recent Onset Arthritis. Clinical, Laboratory and Radiological Findings during the First Year of Disease. The Journal of Rheumatology, 29, 2278-2287.
[16] Sankalé, M., Sow, A.M., Diop, B., Touré, Y.I. and Ruscher, H. (1977) General Features of Rheumatoid Arthritis in Black Africans. Concours Médical, 99, 1103-1112. (In French)
[17] Feldman, D.E., Bernatsky, S., Haggerty, J., et al. (2007) Delay in Consultation with Specialists for Persons with Suspected New-Onset Rheumatoid Arthritis: A Population-Based Study. Arthritis Care & Research, 57, 1419-1425.
http://dx.doi.org/10.1002/art.23086
[18] Dieye, A., Diallo, S., Diatta, M., et al. (1997) Identification of HLA-DR Alleles for Susceptibility to Rheumatoid Polyarthritis in Senegal. Dakar Médical, 42, 111-113.
[19] Mody, G.M. and Meyers, O.L. (1989) Rheumatoid Arthritis in Blacks in South Africa. Annals of the Rheumatic Diseases, 48, 69-72.
http://dx.doi.org/10.1136/ard.48.1.69
[20] Greenwood, B.M. (1969) Polyarthritis in Western Nigeria. I. Rheumatoid Arthritis. Annals of the Rheumatic Diseases, 28, 488-496.
http://dx.doi.org/10.1136/ard.28.5.488
[21] Omar, A., Abo-Elyoun, I., Hussein, H., Nabih, M., Atwa, H., Gad, S., et al. (2013) Anti-Cyclic Citrullinated Peptide (Anti-CCP) Antibody in Juvenile Idiopathic Arthritis (JIA): Correlations with Disease Activity and Severity of Joint Damage (a Multicenter Trial). Joint, Bone, Spine, 80, 38-43.
http://dx.doi.org/10.1016/j.jbspin.2012.03.008

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