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Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Stem Bark of Ceiba pentandra Gaertn

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DOI: 10.4236/pp.2014.512121    3,078 Downloads   3,739 Views   Citations

ABSTRACT

Anti-inflammatory and analgesic effects of the aqueous extract of the stem bark of Ceiba pentandra Gaertn (Bombacaceae) were recorded in rat and mice. Inflammation was induced by carrageenan and cotton pellet. The pain was studied using analgesymeter, Koster and hot plate Methods. Aqueous extract (400 and 800 mg/kg) of Ceiba pentandra presents a significant anti-inflammatory and analgesic activity. Flavono?ds present in the extract seem to be responsible for the activity.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Elion Itou, R. , Sanogo, R. , Etou Ossibi, A. , Nsondé Ntandou, F. , Ondelé, R. , Max Pénemé, B. , Okiémy Andissa, N. , Diallo, D. , Ouamba, J. and Abena, A. (2014) Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Stem Bark of Ceiba pentandra Gaertn. Pharmacology & Pharmacy, 5, 1113-1118. doi: 10.4236/pp.2014.512121.

References

[1] Adjanohoum, E., Ahyi, A.M., Aké Assi, L., et al. (1988) Médecine traditionnelle et pharmacopée. Contribution aux études ethnobotaniques et floristiques en République Populaire du Congo. Edition ACCT, Paris, 605 p.
[2] Longuefosse, J.L. (1995) 100 plantes médicinales de la Caraïbe. Gondwana, 240 p.
[3] Sabih, K., Woods, L.A. and Mitchell, C.L. (1971) Morphine-Induced Hyperalgesia in Rats Tested on the Hot Plate. Journal of Pharmacology and Experimental Therapeutics, 177, 509-513.
[4] Bouquet, A. (1969) Féticheurs et médecine traditionnelle du Congo Brazzaville. ORSTOM 36, 980 p.
[5] Fábio, G.G.M., Jeane, C.V., Ivana, A.N.A., et al. (2001) Antinociceptive and Antiedematogenic Properties and Acute Toxicity of Tabebuia avellanedae Lor. ex Griseb. Inner Bark Aqueous Extract. BMC Pharmacology, 1, 6.
http://dx.doi.org/10.1186/1471-2210-1-6
[6] Guirimand, F. (2003) Physiologie de la douleur: Données récentes Version. Néphrologie, 24, 401-407.
[7] Ibara, J.R., Elion Itou, R.D.G., Etou Ossibi, A., et al. (2007) Enquête ethnobotanique à propos de plantes médicinales Congolaise présumées anti-ulcéreuses. Phytothérapia, 5, 118-120.
http://dx.doi.org/10.1007/s10298-007-0236-4
[8] Kabangu, K. (1990) Eléments de phytothérapie comparée: Plantes médicinales africaines. Centre de recherches pédagogiques de Kinshasa, 196 p.
[9] Borgi, W., Ghedira, K. and Chouchane, N. (2007) Antiinflammatory and analgesic activities of Zizyphus lotus root barks. Phitoterapia, 78, 16-19.
[10] Mossa, A.C., Rafatulalah, S., Galal, A.M., et al. (1995) Pharmacological Studies of Rhus retinorrha. International Journal of Pharmacognosy, 33, 242-246.
http://dx.doi.org/10.3109/13880209509065371
[11] Kissin, I., Cheryl, A., et al. (2000) Acute Tolerance to Continuously Infused Alfentanil: The Role of Cholecystokinin and N-Methyl-D-Aspartate-Nitric Oxide Systems. Anesthesia & Analgesia, 91, 110-116.
[12] Koster, R. and Anderson, M. (1959) Acetic Acid for Analgesic Screening. Federation Proceedings, 18, 412.
[13] Laurent, P.E. and Pérrin, L.F. (1987) Inflammation-Physiopatologie UPSA (Laboratoires), 80 p.
[14] Nsonde Ntandou, G.F., Banzouzi, J.T., Mbatchi, B. et al. (2010) Analgesic and Anti-Inflammatory Effects of Cassia siamea Lam. Stem Bark Extracts. Journal of Ethnopharmacology, 127, 108-111.
http://dx.doi.org/10.1016/j.jep.2009.09.040

  
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