Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Stem Bark of Ceiba pentandra Gaertn

Romaric De Garde Elion Itou¹, Rokia Sanogo², Arnaud Wilfrid Etou Ossibi¹, Freddy Gelase Nsondé Ntandou¹, Radard Ondelé¹, Bonaventure Max Pénemé¹, Nadége Okiémy Andissa¹, Drissa Diallo², Jean Maurille Ouamba³, Ange Antoine Abena¹

¹Laboratoire de Biochimie et Pharmacologie, Faculté des Sciences de la Santé, Université Marien Ngouabi, Brazzaville, Congo.
²Département Médecine Traditionnelle (DMT), Faculté de Médecine, de Pharmacie et d’Odonto-Stomatologie,Université de Bamako, Bamako, Mali.
³Unité de Chimie du Végétale et de la vie, Faculté des Sciences et Techniques, Université Marien Ngouabi, Brazzaville, Congo.

DOI: 10.4236/pp.2014.512121                

Abstract

Anti-inflammatory and analgesic effects of the aqueous extract of the stem bark of Ceiba pentandra Gaertn (Bombacaceae) were recorded in rat and mice. Inflammation was induced by carrageenan and cotton pellet. The pain was studied using analgesymeter, Koster and hot plate Methods. Aqueous extract (400 and 800 mg/kg) of Ceiba pentandra presents a significant anti-inflammatory and analgesic activity. Flavono?ds present in the extract seem to be responsible for the activity.

Keywords

Analgesic, Anti-Inflammatory, Ceiba pentandra

Conflicts of Interest

The authors declare no conflicts of interest.

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