Upper Gastrointestinal Bleeding at a Public Referal Hospital in Malawi

Abstract

Background: Upper gastrointestinal bleeding (UGIB) is a medical emergency. Timely and appropriate treatment can be lifesaving. Where medical equipment and supplies are inadequate, management of upper gastrointestinal bleeding is challenging. Methods: A retrospective review of charts of patients who were admitted during the year 2010, with a diagnosis of Upper Gastrointestinal Bleeding (UGIB), was done at Kamuzu Central Hospital, Lilongwe, Malawi. A Rockall score was applied to determine mortality risk. Results: A total number of 187 records (119 men and 68 women, mean age of 40.7 ± 15.3 years) were reviewed. The mortality rate was 23.5%, with a non-significant gender difference. Bleeding oesophageal varices were the most common clinical cause of UGIB (42.8%), with more males (63.1%) than females affected. About 40% of patients had no cause of UGIB indicated in their records. 14 (7.5%) patients had a normal oesophagogastroduodenoscopy (OGD). Oesophageal tumor was present in 2.7% of the subjects as a cause of UGIB. Access to endoscopy, for diagnosis and therapeutic intervention, and surgery (Hassab procedure) was available to less than 50% of the patients. Sixteen patients (9.5%) had surgery after endoscopy due to lack of variceal banding materials. Conclusion: Upper gastrointestinal bleeding is an important and common clinical problem at Kamuzu Central Hospital. Oesophageal varices seem to be the commonest cause of UGIB. Inadequacy of resuscitation materials and perhaps timely diagnostic and therapeutic endoscopic and surgical interventions are important limiting factors to favourable patient outcome. Work towards regular provision and supply of interventional resources regarding UGIB management may improve patient outcome.

Share and Cite:

Mulima, G. , Qureshi, J. , Shores, C. , Tamimi, S. , Klackenberg, H. and Andrén-Sandberg, Å. (2014) Upper Gastrointestinal Bleeding at a Public Referal Hospital in Malawi. Surgical Science, 5, 501-507. doi: 10.4236/ss.2014.511077.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Depolo, A., Dobrila-Dintinjana, R., Uravi, M., Grbas, H. and Rubini, M. (2001) Upper Gastrointestinal Bleeding— Review of Our Ten Years Results. Zentralblatt für Chirurgie, 126, 772-776.
http://dx.doi.org/10.1055/s-2001-18265
[2] van Leerdam, M.E. (2008) Epidemiology of Acute Upper Gastrointestinal Bleeding. Best Practice & Research Clinical Gastroenterology, 22, 209-224. http://dx.doi.org/10.1016/j.bpg.2007.10.011
[3] Mwanahawa, S.S.M., Charles, M.M. and Gibson, S.K. (2010) The Aetiology, Management and Clinical Outcome of Upper Gastrointestinal Bleeding among Patients Admitted at Kilimanjaro Christian Medical Centre in Moshi, Tanzania. Tanzania Journal of Health Research, 12, 286-289.
[4] Harries, A.D. and Wirima, J. (1989) Upper Gastrointestinal Bleeding in Malawian Adults and Value of Splenomegaly in Predicting Source of Haemorrhage. East African Medical Journal, 66, 97-99.
[5] http://www.who.int/water_sanihisto/en/tation_health/diseases/sc
[6] Hassab, M.A. (1970) Nonshunt Operations in Portal Hypertension without Cirrhosis. Surg Gynecol Obstet, 131, 648-654.
[7] http://en.wikipedia.org/wiki/Kamuzu_Central_Hospital
[8] Rockall, T.A., Logan, R.F., Devlin, H.B. and Northfield, T.C. (1996) Risk Assessment after Acute Upper Gastrointestinal Haemorrhage. Gut, 38, 316-321. http://dx.doi.org/10.1136/gut.38.3.316
[9] Harris, P.A., Taylor, R., Thielke, R., Payne, J., Gonzalez, N. and Conde, J.G. (2009) Research Electronic Data Capture (REDCap)—A Metadata-Driven Methodology and Workflow Process for Providing Translational Research Informatics Support. Journal of Biomedical Informatics, 42, 377-381.
[10] Tijjani, B.M., Borodo, M.M. and Samaila, A.A. (2009) Endoscopic Findings in Patients with Upper Gastrointestinal Bleeding in Kano, North-Western Nigeria. Nigerian Hospital Practice, 4.
[11] Suba, M., Mtabho, C. and Kibiki, G.S. (2010) The Aetiology, Management and Clinical Outcome of Upper Gastrointestinal Bleeding. Tanzani Journal of Health Research, 12, 286-289.
[12] Wolf, L.L., Ibrahim, R., Miao, C., Muyco, A., Hosseinipour, M.C. and Shores, C. (2012) Esophagogastroduodenoscopy in a Public Referral Hospital in Lilongwe, Malawi: Spectrum of Disease and Associated Risk Factors. World Journal of Surgery, 36, 1074-1082.
http://dx.doi.org/10.1007/s00268-012-1490-7
[13] Makdissi, F.F., Herman, P., Pugliese, V., Cleva, R., Saad, W.A., Cecconello, I., et al. (2010) Long-Term Results of Esophagogastric Devascularization and Splenectomy Associated with Endoscopic Treatment in Schistosomal Portal Hypertension. World Journal of Surgery, 34, 2682-2688.
http://dx.doi.org/10.1007/s00268-010-0717-8
[14] Wilkins, T., Khan, N., Nabh, A. and Schade, R.R. (2012) Diagnosis and Management of Upper Gastrointestinal Bleeding. American Family Physician, 85, 469-476.

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.