Comparison of Established Risk Factors among Type 2 Diabetic Patients with or without Retinopathy in Golestan Hospital, Ahvaz 2010


The aim of this study was to establish diabetic retinopathy correlation with several risk factors. A prospective study including 256 type II diabetic patients who referred to diabetes’s clinic was designed. All patients underwent physical & retina examination and then completed questionnaire including duration of DM, cardiovascular disease, stroke, chronic kidney disease, smoking, and kind of treatment, blood pressure, BMI, abdominal & hip circumference. Results of HbA1C, total cholesterol, HDL & LDL cholesterol, TG, FBS, creatinine, 24-h urine microalbumin were recorded. Data were analyzed by SPSS version 17 with K2, independent samples T, and logistic regression. Of 256 types II diabetic patients 81 & 175 were men and women respectively. Mean age of subject was 54 ± 10.27. Prevalence of diabetic retinopathy was 22.3% & macula edema 0.5% & PDR 6% & NPDR 14%; diabetic retinopathy was associated with duration of DM & BMI (P = 0, P = 0.43 respectively). Mean of FBS 191 ± 83 vs. 165.7 ± 74.5 (P = 0.03), HbA1c 9.1 ± 2 vs. 8.5 ± 1.9 (P = 0.02), 24-h urine microalbumin 181.2 ± 404.7 vs. 60.2 ± 236 (P = 0.03), Systolic blood pressure 124.3 ± 21.3 vs. 118.5 ± 17.8 (p = 0.04) differed between diabetic patients with or without diabetic retinopathy. There were no significant difference between subject with & without diabetic retinopathy in total cholesterol LDL, HDL, TG, Cr, Diastolic BP, types of treatment, cardiovascular disease, chronic kidney disease, stroke & smoking. This study showed prevalence of diabetic retinopathy was high and it associated with duration of DM, BMI, FBS, HbA1C, 24-h urine albumin, and systolic blood pressure.

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Rashidi, H. , Kasiri, A. , Latifi, S. , Zaman, F. , Shahbazian, H. and Aleali, A. (2014) Comparison of Established Risk Factors among Type 2 Diabetic Patients with or without Retinopathy in Golestan Hospital, Ahvaz 2010. Open Journal of Endocrine and Metabolic Diseases, 4, 225-229. doi: 10.4236/ojemd.2014.410022.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Cugati, S., Kifley, A., Mitchell, P. and Wang, J.J. (2006) Temporal Trends in the Age-Specific Prevalence of Diabetes and Diabetic Retinopathy in Older Persons: Population-Based Survey Findings. Diabetes Research and Clinical Practice, 74, 301-308.
[2] Candrilli, S.D., Davis, K.L., Kan, H.J., Lucero, M.A. and Rousculp, M.D. (2007) Prevalence and the Associated Burden of Illness of Symptoms of Diabetic Peripheral Neuropathy and Diabetic Retinopathy. Journal of Diabetes and its Complications, 21, 306-314.
[3] Wang, F.H., Liang, Y.B., Zhang, F., Wang, J.J., Wei, W.B. and Tao, Q.S. (2009) Prevalence of Diabetic Retinopathy in Rural China: The Handan Eye Study. Ophthalmology, 116, 461-467.
[4] Wong, T.Y., Cheung, N., Tay, W.T., Wang, J.J., Aung, T. and Saw, S.M. (2008) Prevalence and Risk Factors for Diabetic Retinopathy: The Singapore Malay Eye Study. Ophthalmology, 115, 1869-1875.
[5] Olafsdottir, E., Andersson, D.K., Dedorsson, I. and Stefánsson, E. (2014) The Prevalence of Retinopathy in Subjects with and without Type 2 Diabetes Mellitus. Acta Ophthalmologica, 92, 133-137.
[6] Targher, G., Bertolini, L., Zenari, L., Lippi, G., Pichiri, I. and Zoppini, G. (2008) Diabetic Retinopathy Is Associated with an Increased Incidence of Cardiovascular Events in Type 2 Diabetic Patients. Diabetic Medicine, 25, 45-50.
[7] Ramavat, P.R., Ramavat, M.R., Ghugare, B.W., Vaishnav, R.G. and Joshi, M.U. (2013) Prevalence of Diabetic Retinopathy in Western Indian Type 2 Diabetic Population: A Hospital-Based Cross-Sectional Study. Journal of Clinical and Diagnostic Research, 7, 1387-1390.
[8] Rema, M., Premkumar, S., Anitha, B., Deepa, R., Pradeepa, R. and Mohan, V. (2005) Prevalence of Diabetic Retinopathy in Urban India: The Chennai Urban Rural Epidemiology Study (CURES) Eye Study, I. Investigative Ophthalmology & Visual Science, 46, 2328-2333.
[9] Mohamed, Q., Gillies, M.C. and Wong, T.Y. (2007) Management of Diabetic Retinopathy: A Systematic Review. JAMA, 298, 902-916.
[10] Keech, A.C., Mitchell, P., Summanen, P.A., O’Day, J., Davis, T.M. and Moffitt, M.S. (2007) Effect of Fenofibrate on the Need for Laser Treatment for Diabetic Retinopathy (FIELD Study): A Randomised Controlled Trial. The Lancet, 370, 1687-1697.
[11] He, B.B., Wei, L., Gu, Y.J., Han, J.F., Li, M. and Liu, Y.X. (2012) Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus. International Journal of Endocrinology, 2012, Article ID: 157940.
[12] Rafati, N., Dehghan, M.H., Javadi, M.A., Souri, H., Zaeri, F. and Gooya, M.M. (2008) The Prevalence of Diabetic Retinopathy in Tehran Province. BMC Ophthalmology, 13, 166-175.

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