Sporadic Desmoid Tumor of the Small Bowel Mesentery in a Male Patient: A Case Report and Literature Review

Abstract

Aggressive fibromatosis arising from the small bowel mesentery is extremely rare. It may occur in association with previous trauma, abdominal surgery, drugs, Gardner’s syndrome, or familial adenomatous polyposis. This paper presents a 32-year-old man with no significant medical or surgical history, complaining of diffuse abdominal pain and discomfort. His computed tomography scan revealed a well-defined soft tissue mass in the peritoneal cavity. He underwent surgical excision of the mass with resection and anastomosis of the involved loop of the small intestine. Histological examination confirmed mesenteric fibromatosis without infiltration of the bowel. The patient remained well during the 8 months follow-up.

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Amaadour, L. , Benbrahim, Z. , Benhayoune, K. , Chbani, L. , Arifi, S. and Mellas, N. (2014) Sporadic Desmoid Tumor of the Small Bowel Mesentery in a Male Patient: A Case Report and Literature Review. Journal of Cancer Therapy, 5, 1000-1004. doi: 10.4236/jct.2014.511104.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Guglielmi, G., Cifaratti, A., Scalzo, G. and Magarelli, N. (2009) Imaging of Superficial and Deep Fibromatosis. Radiologia Medica, 114, 1292-1307. http://dx.doi.org/10.1007/s11547-009-0458-7
[2] Escobar, C., Munker, R., Thomas, J.O., Li, B.D. and Burton, G.V. (2012) Update on Desmoid Tumors. Annals of Oncology, 23, 562-569. http://dx.doi.org/10.1093/annonc/mdr386
[3] Faria, S.C., Iyer, R.B., Rashid, A., Ellis, L. and Whitman, G.J. (2004) Desmoid Tumor of the Small Bowel and the Mesentery. American Journal of Roentgenology, 183, 118.
http://dx.doi.org/10.2214/ajr.183.1.1830118
[4] Lath, C., Khanna, P.C., Gadewar, S.B. and Agrawal, D. (2006) Inoperable Aggressive Mesenteric Fibromatosis with Ureteric Fistula. Case Report and Literature Review. European Journal of Radiology, 59, 117-121. http://dx.doi.org/10.1016/j.ejrad.2005.12.036
[5] Kabra, V., Chaturvedi, P., Pathak, K.A. and de Souza, L.J. (2001) Mesenteric Fibromatosis: A Report of Three Cases and Literature Review. Indian Journal of Cancer, 38, 133-136.
[6] Burke, A.P., Sobin, L.H., Shekitka, K.M., Federspiel, B.H. and Helwig, E.B. (1990) Intra-Abdominal Fibromatosis. A Pathologic Analysis of 130 Tumors with Comparison of Clinical Subgroups. The American Journal of Surgical Pathology, 14, 335-341.
http://dx.doi.org/10.1097/00000478-199004000-00004
[7] Reitamo, J.J., Hayry, P., Nykyri, E. and Saxen, E. (1982) The Desmoids Tumor. I: Incidence, Sex-, Age and Anatomical Distribution in the Finnish Population. The American Journal of Clinical Pathology, 77, 665-673.
[8] Yang, C.H., Sheen-Chen, S.M., Lu, C.C., Ko, S.F. and Eng, H.L. (2005) Computed Tomographic Presentation of Mesenteric Fibromatosis. Digestive Diseases and Sciences, 50, 348-350.
http://dx.doi.org/10.1007/s10620-005-1609-x
[9] McCormack, D., Kesha, K., Tittle, S.L. and Saldinger, P.F. (2010) Mesenteric Fibromatosis Mimicking a Gastrointestinal Stromal Tumor. Connecticut Medicine, 74, 197-200.
[10] Reitano, J.J., Scheinin, T.M. and Hayry, P. (1986) The Desmoid Syndrome: New Aspects in the Cause, Pathogenesis and Treatment of the Desmoid Tumor. The American Journal of Surgery, 151, 230-237. http://dx.doi.org/10.1016/0002-9610(86)90076-0
[11] Stout, A.P. (1961) The Fibromatosis. Clinical Orthopaedics and Related Research, 19, 11-18.
[12] Zhang, Z.L., Liang, C.H., Liu, Y.B., et al. (2010) Computed Tomography and Magnetic Resonance Imaging Features of Desmoid-Type Fibromatosis: Comparison with the Pathological Findings. 30, 2495-2497.
[13] Guglielmi, G., Cifaratti, A., Scalzo, G., et al. (2009) Imaging of Superficial and Deep Fibromatosis. Radiologia Medica, 114, 1292-1307. http://dx.doi.org/10.1007/s11547-009-0458-7
[14] Casillas, J., Sais, G.J., Greve, J.L., Iparraguirre, M.C. and Morillo, G. (1991) Imaging of Intra and Extra Abdominal Desmoid Tumors. Radiographics, 11, 959-968.
http://dx.doi.org/10.1148/radiographics.11.6.1749859
[15] Healy, J.C., Reznek, R.H., Clark, S.K., Phillips, R.K. and Armstrong, P.M.R. (1997) Appearances of Desmoid Tumors in Familial Adenomatous Polyposis. American Journal of Roentgenology, 169, 465-472. http://dx.doi.org/10.2214/ajr.169.2.9242755
[16] Rodriguez, J.A., Guarda, L.A. and Rosai, J. (2004) Mesenteric Fibromatosis with Involvement of the Gastrointestinal Tract. A GIST Simulator: A Study of 25 Cases. The American Journal of Clinical Pathology, 121, 93-98. http://dx.doi.org/10.1309/59VAH0KVF53WB633
[17] Carlson, J.W. and Fletcher, C.D. (2007) Immunohistochemistry for Beta-Catenin in the Differential Diagnosis of Spindle Cell Lesions: Analysis of a Series and Review of the Literature. Histopathology, 51, 509-514. http://dx.doi.org/10.1111/j.1365-2559.2007.02794.x
[18] Hailemariam, S., Jaeger, P., Goebel, N. and Grant, J.W. (1988) Mesenteric Fibromatosis with Ureteric Stenosis. Postgraduate Medical Journal, 64, 79-81. http://dx.doi.org/10.1136/pgmj.64.747.79
[19] Smith, A.J., Lewis, J.J., Merchant, N.B., Leung, D.H., Woodruff, J.M. and Brennan, M.F. (2000) Surgical Management of Intra-Abdominal Desmoids Tumours. British Journal of Surgery, 87, 608-613. http://dx.doi.org/10.1046/j.1365-2168.2000.01400.x
[20] Fiore, M., Rimareix, F., Mariani, L., et al. (2009) Desmoid-Type Fibromatosis: A Front-Line Conservative Approach to Select Patients for Surgical Treatment. Annals of Surgical Oncology, 16, 2587-2593.
http://dx.doi.org/10.1245/s10434-009-0586-2
[21] National Comprehensive Cancer Network (NCCN) (2014) Guidelines for Soft Tissue Sarcomas, Version 2. www.nccn.org
[22] Tonelli, F., Ficari, F., Valanzano, R. and Brandi, M.L. (2003) Treatment of Desmoids and Mesenteric Fibromatosis in Familial Adenomatous Polyposis with Raloxifene. Tumori, 89, 391-396.
[23] Yantiss, R.K., Spiro, I.J., Compton, C.C. and Rosenberg, A.E. (2000) Gastrointestinal Stromal Tumor versus Intra-Abdominal Fibromatosis of the Bowel Wall: A Clinically Important Differential Diagnosis. The American Journal of Surgical Pathology, 24, 947-957. http://dx.doi.org/10.1097/00000478-200007000-00006
[24] Ng, T.Y., Yang, M.D., Chen, Y.F. and Chang, C.H. (2007) Resolution of Hydronephrosis Due to Massive Mesenteric Fibromatosis Using Cyclo-Oxygenase 2 Inhibitors. Urology, 70, 591.e3-591.e4.

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