Synthesis of a Rhodamine-Appended Cyclophane as a Fluorescence Host in Water


A cationic water-soluble cyclophane (1a) having a rhodamine moiety as a red-fluorescence fluorophore was prepared by reaction of a monoamine derivative of tetraaza[]paracyclophane having three N-t-butoxycarbonyl-β-alanine residues with rhodamine B isothiocyanate, followed by removal of the protecting groups. The guest-binding behavior of 1a toward anionic guests such as dabsyl derivative and 4-(1-pyrene)butanoate was investigated by fluorescence spectroscopy. The results suggested the formation of host-guest complexes with a stoichiometric ratio of 1:1 and the binding constants (K) of the host-guest complexes were evaluated.

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Hayashida, O. and Kaku, Y. (2014) Synthesis of a Rhodamine-Appended Cyclophane as a Fluorescence Host in Water. Advances in Chemical Engineering and Science, 4, 401-408. doi: 10.4236/aces.2014.44044.

Conflicts of Interest

The authors declare no conflicts of interest.


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