Intravascular Papillary Endothelial Hyperplasia: A Rare Vascular Lesion Affecting Submandibular and Sublingual Region

Zhenq Xu¹, Li Long¹, Jianch Zhang¹, Ruiy Chen², Nan Yang³, Ping Zhang^1*

¹Department of Oral and Maxillofacial Surgery, Tianjin Stomatology Hospital of Nankai University, Tianjin, China.
²Department of Oral Pathology, Tianjin Stomatology Hospital of Nankai University, Tianjin, China.
³Department of Nursing, Tianjin Stomatology Hospital of Nankai University, Tianjin, China.

DOI: 10.4236/ojst.2014.49063                

Abstract

Intravascular papillary endothelial hyperplasia is an unusual benign vascular lesion of the skin and subcutaneous tissue consisting of papillary formations lined with proliferative endothelial cells. The clinical characteristic is not specific and the diagnosis is based on histological examination. The lesion is often mistaken for angiosarcoma and a group of other benign and malignant vascular lesions. IPEH has been relatively rarely described in the head and neck region. An uncommon case located in the submandibular and sublingual region is presented which was misinterpreted as venous malformations and malignant tumors of vascular origin initially. A surgical excision was performed and no recurrences have been found after 5 years of follow-up.

Keywords

Intravascular Papillary Endothelial Hyperplasia, Submandibular and Sublingual Region, Angiosarcoma, Venous Malformation

Conflicts of Interest

The authors declare no conflicts of interest.

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