A Case of Oral Squamous Cell Carcinoma with Scattered Metastases

DOI: 10.4236/ojrad.2014.43035   PDF   HTML     3,116 Downloads   3,836 Views  


We experienced a case of oral squamous cell carcinoma of the mandible with scattered distant metastases. After neoadjuvant chemoradiotherapy, the patient underwent segmental resection of the right mandible and right radical neck dissection. Surgical specimens confirmed remarkable nodal metastases. Unfortunately, the patient experienced a rapid fatal outcome, and numerous distant metastases were detected on autopsy. Moreover, postoperative 18F-fluorodeoxyglucose- positron emission tomography/computed tomography detected systemic distant metastases in this case. In our opinion, the use of preoperative FDG-PET/CT should be considered for patients with suspected poor prognoses.

Share and Cite:

Aragaki, T. , Michi, Y. , Nakamura, S. , Toriihara, A. , Kayamori, K. , Harada, K. and Kurabayashi, T. (2014) A Case of Oral Squamous Cell Carcinoma with Scattered Metastases. Open Journal of Radiology, 4, 270-274. doi: 10.4236/ojrad.2014.43035.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Kowalski, L.P., Bagietto, R., Lara, J.R., Santos, R.L., Silva, J.F. and Magrin, J. (2000) Prognostic Significance of the Distribution of Neck Node Metastasis from Oral Carcinoma. Head & Neck, 22, 207-214.
[2] Lonneux, M., Hamoir, M., Reychler, H., Maingon, P., Duvillard, C., Calais, G., et al. (2010) Positron Emission Tomography with [18F]Fluorodeoxyglucose Improves Staging and Patient Management in Patients with Head and Neck Squamous Cell Carcinoma: A Multicenter Prospective Study. Journal of Clinical Oncology, 28, 1190-1195.
[3] Veit-Haibach, P., Luczak, C., Wanke, I., Fischer, M., Egelhof, T., Beyer, T., et al. (2007) TNM Staging with FDGPET/CT in Patients with Primary Head and Neck Cancer. European Journal of Nuclear Medicine and Molecular Imaging, 34, 1953-1962.
[4] Goerres, G.W., Schmid, D.T., Gr?tz, K.W., Von Schulthess, G.K. and Eyrich, G.K. (2003) Impact of Whole Body Positron Emission Tomography on Initial Staging and Therapy in Patients with Squamous Cell Carcinoma of the Oral Cavity. Oral Oncology, 39, 547-551.
[5] Ferlito, A., Shaha, A.R., Silver, C.E., Rinaldo, A. and Mondin, V. (2001) Incidence and Sites of Distant Metastases from Head and Neck Cancer. ORL, 63, 202-207.
[6] van den Brekel, M.W., Stel, H.V., Castelijns, J.A., Nauta, J.J., van der Waal, I., Valk, J., et al. (1990) Cervical Lymph Node Metastasis: Assessment of Radiologic Criteria. Radiology, 177, 379-384.
[7] van den Brekel, M.W., Castelijns, J.A. and Snow, G.B. (1994) Detection of Lymph Node Metastases in the Neck: Radiologic Criteria. Radiology, 192, 617-618.
[8] Nagata, S., Ota, K., Nagata, M. and Shinohara, M. (2012) Cardiac Metastasis of Head and Neck Squamous Cell Carcinoma. International Journal of Oral and Maxillofacial Surgery, 41, 1458-1462.
[9] Rohren, E.M., Turkington, T.G. and Coleman, R.E. (2004) Radiology Clinical Applications of PET in Oncology. Radiology, 231, 305-332.
[10] Bybel, B., Brunken, R.C., Shah, S.N., Wu, G., Turbiner, E. and Neumann, D.R. (2006) PET and PET/CT Imaging: What Clinicians Need to Know. Cleveland Clinic Journal of Medicine, 73, 1075-1087.
[11] Sch?der, H., Yeung, H.W., Gonen, M., Kraus, D. and Larson, S.M. (2004) Head and Neck Cancer: Clinical Usefulness and Accuracy of PET/CT Image Fusion. Radiology, 231, 65-72.
[12] Michikawa, C., Uzawa, N., Kayamori, K., Sonoda, I., Ohyama, Y., Okada, N., et al. (2012) Clinical Significance of Lymphatic and Blood Vessel Invasion in Oral Tongue Squamous Cell Carcinomas. Oral Oncology, 48, 320-324.

comments powered by Disqus

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.