Update of Aetiological Patterns of Adult Gastric Outlet Obstruction in Accra, Ghana

Abstract

Background: The aetiology of gastric outlet obstruction globally has evolved from benign to malignant causes, but there seem to be no recent data on the trends in Ghana. The aim was, therefore, to identify the current patterns in the aetiology of gastric outlet obstruction in the adult population in Ghana. Methodology: This was a retrospective review of all confirmed cases of gastric outlet obstruction in the last decade, spanning from June 2004 to May 2014, that were managed at the Korle Bu Teaching Hospital. Results: A total of 107 patients were managed for gastric outlet obstruction with a male to female ratio of 2.15:1 and most of the patients making 71.3% of cases belonged to the age range of 40 to 60 years. The predominant aetiology for gastric outlet obstruction was found to be gastric cancer (55.140%), followed by peptic ulcer disease (27.103%). Conclusion: The aetiology of gastric outlet obstruction in Ghana has evolved from benign to malignant causes, following current global trends. Gastric cancer is now the most important cause of gastric outlet obstruction in Ghana, followed by peptic ulcer disease which predominates as the commonest benign cause.

Share and Cite:

Essoun, S. and Dakubo, J. (2014) Update of Aetiological Patterns of Adult Gastric Outlet Obstruction in Accra, Ghana. International Journal of Clinical Medicine, 5, 1059-1064. doi: 10.4236/ijcm.2014.517136.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Tendler, D.A. (2002) Malignant Gastric Outlet Obstruction: Bridging Another Divide. The American Journal of Gastroenterology, 97, 4-6.
http://dx.doi.org/10.1111/j.1572-0241.2002.05391.x
[2] Samad, A, Whanzada, T.W. and Shoukat, I. (2007) Gastric Outlet Obstruction: Change in Etiology. Pakistan Journal of Surgery, 23, 29-32.
[3] Johnson, C.D. (1995) Gastric Outlet Obstruction-Malignant until Proven Otherwise. The American Journal of Gastroenterology, 90, 1740.
[4] Shone, D.N., Nikoomanesh, P., Smith-Meek, M.M. and Bender, J.S. (1995) Malignancy Is the Most Common Cause Of Gastric Outlet Obstruction in the Era of H2 Blockers. The American Journal of Gastroenterology, 90, 1769-1770.
[5] Johnson, C.D. and Ellis, H. (1990) Gastric Outlet Obstruction Now Predicts Malignancy. British Journal of Surgery, 77, 1023-1024.
http://dx.doi.org/10.1002/bjs.1800770923
[6] Chowdhury, A., Dhali, G.K. and Banerjee, P.K. (1996) Etiology of Gastric Outlet Obstruction. The American Journal of Gastroenterology, 91, 1679.
[7] Badoe, E.A. (1972) Gastric Outlet Obstruction in Adults—Ktrle Bu Teaching Hospital, Accra. The West African Medical Journal and Nigerian Medical & Dental Practitioner, 21, 154-158.
[8] Sohn, T.A., Lillemoe, K.D. and Cameron, J.L. (1999) Surgical Palliation of Unresectable Periampullary Adenocarcinoma in the 1990s. Journal of the American College of Surgeons, 188, 658-666.
http://dx.doi.org/10.1016/S1072-7515(99)00049-6
[9] Misra, S.P., Dwivedi, M. and Misra, V. (1998) Malignancy Is the Most Common Cause of Gastric Outlet Obstruction Even in a Developing Country. Endoscopy, 30, 484-486.
http://dx.doi.org/10.1055/s-2007-1001313
[10] Jaka, H., Mchembe, M.D., Rambau, P.F. and Chalya, P.L. (2013) Gastric Outlet Obstruction at Bugando Medical Centre in Northwestern Tanzania: A Prospective Review of 184 Cases. BMC Surgery, 13, 41.
http://dx.doi.org/10.1186/1471-2482-13-41
[11] Ostrow, B. (2007) Peptic Ulcer Disease—The Impact of Helicobacter pylori on Management in the Developing World. Surgery in Africa Monthly Review (SIA), No. 9, April 2007 Edition.
[12] Taskin, V., Gurer, I., Ozyilkan, E., Sare, M. and Hilmioglu, F. (2000) Effect of Helicobacter pylori Eradication on Peptic Ulcer Disease Complicated with Outlet Obstruction. Helicobacter, 5, 38-40.
http://dx.doi.org/10.1046/j.1523-5378.2000.00005.x
[13] Ghana Statistical Service (GSS) (2012) 2010 Population and Housing Census, Summary Report of Final Results.

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.