Combination of the MODS Assay with the SensititreTM MYCOTB Plate for Rapid Detection of MDR- and XDR-TB

Abstract

We combined the new SensititreTM MYCOTB test with the MODS assay for detection of MDR- and XDR-TB. Categorical agreement of the MODS assay with the critical concentrations at 3 days of incubation was highest for INH (91.4%) and RIF (100%) and at 5 days 86.7% and 94.6% for the fluoroquinolones and aminoglycosides, respectively. By combining these two methods, it is possible to identify MDR-TB in as little as 3 days and XDR- or pre-XDR-TB within 5 days.

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Salee, P. , Harrison, L. , Dionne, K. , McArthur, C. and Parrish, N. (2014) Combination of the MODS Assay with the SensititreTM MYCOTB Plate for Rapid Detection of MDR- and XDR-TB. Journal of Tuberculosis Research, 2, 101-105. doi: 10.4236/jtr.2014.23012.

Conflicts of Interest

The authors declare no conflicts of interest.

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