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Dehydrosulfurization of Aromatic Thioamides to Nitriles Using Indium(III) Triflate

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DOI: 10.4236/ijoc.2014.43018    2,823 Downloads   3,365 Views   Citations

ABSTRACT

The efficient dehydrosulfurization of thioamides to nitriles was carried out using indium(III) triflate as a catalyst. Based on the results of the initial study, the optimal reaction conditions required 5 mol% of indium(III) triflate with toluene as the practical solvent. Various thioamides were successfully converted to nitriles in high yields.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Mineno, T. , Takebe, Y. , Tanaka, C. and Mashimo, S. (2014) Dehydrosulfurization of Aromatic Thioamides to Nitriles Using Indium(III) Triflate. International Journal of Organic Chemistry, 4, 169-173. doi: 10.4236/ijoc.2014.43018.

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