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The Role of Gallium (Ga-67) Scintigraphy in the Diagnosis of Sarcoidosis

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DOI: 10.4236/mri.2014.33012    3,419 Downloads   4,139 Views   Citations

ABSTRACT

Purpose: To identify and interrogate the role of Gallium-67 scintigraphy in the diagnosis of Sarcoidosis. Methods: A retrospective study of 75 patients with suspected Sarcoidosis in a large teaching hospital with a specialist Sarcoidosis Centre. Results: Ga-67 scintigraphy in patients considered on clinical grounds to have Sarcoidosis is a useful and sensitive test, and furthermore, by relaxing the interpretation of gallium scintigraphy sensitivity may be increased (from 20% to 80%) for a relatively small drop in specificity. Conclusions: The sensitivity of diagnostic power may be increased with a change in diagnostic criteria at the expense of only a small drop in specificity. In the context of Neurosarcoidosis, our results support the theory that Ga-67 scintigraphy has value in identifying potential, asymptomatic biopsy sites outside of the CNS that may not be identified by other forms of imaging.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Allard, A. , Buscombe, J. and Kidd, D. (2014) The Role of Gallium (Ga-67) Scintigraphy in the Diagnosis of Sarcoidosis. Modern Research in Inflammation, 3, 99-107. doi: 10.4236/mri.2014.33012.

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