Age and Gender Differences in Cytokine Profile of Lymph and Blood Serum


We studied the cytokine profile (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-10, GM-CSF, interferon-γ, TNFα,) of the lymph, blood serum and conditioned medium of the lymph cells of Wistar rats. It was found that the concentration of cytokines investigated in the lymph of Wistar rats was significantly higher compared to the serum. Age and gender differences between the concentration of pro- and anti-inflammatory cytokines in the lymph and blood serum were found. The concentration of the cytokines was determined using the test system “Bio-Rad”.

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Poveshchenko, A. , Orlov, N. , Kazakov, O. , Poveshchenko, O. , Kim, I. , Bondarenko, N. , Miller, T. , Strunkin, D. , Kabakov, A. , Reiter, T. and Konenkov, V. (2014) Age and Gender Differences in Cytokine Profile of Lymph and Blood Serum. Advances in Aging Research, 3, 216-221. doi: 10.4236/aar.2014.33030.

Conflicts of Interest

The authors declare no conflicts of interest.


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