Nano-γ-Fe₂O₃: Efficient, Reusable and Green Catalyst for N-tert-Butoxycarbonylation of Amines in Water

Venkataramana Medisetti, Umadevi Parimi, Ramesh Babu Anagani, K. V. V. V. Satyanarayana

Department of Chemistry, Acharya Nagarjuna University, Guntur, India.
Department of Chemistry, Gitam University, Visakhapatnam, India.

DOI: 10.4236/gsc.2014.42014                

Abstract

An efficient and versatile practical protocol for the chemoselective N-tert-butoxycarbonylation of amines using Nano-γ-Fe₂O₃ and (BOC)₂O. Nano-γ-Fe₂O₃ was applied as an efficient, green, heterogeneous and reusable catalyst at ambient temperature; the method is general for the preparation of N-Boc derivatives of aliphatic, heterocyclic, aromatic as well as amino acid derivatives.

Keywords

Nano-γ-Fe₂O₃, N-Boc Protection, Amine, Heterogeneous Catalyst, Water

Conflicts of Interest

The authors declare no conflicts of interest.

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