Antidermatophytic Activity of Essential Oils against Locally Isolated Microsporum canis—Gaza Strip


There is a need for new antimicrobial drugs due to the continuous development of resistance. Natural antimicrobials are of utmost importance due to safety issue and availability. The antifungal activity of four essential oils (Mentha piperta, Thymus vulgaris, Cymbopogon citratus, and Oreganum majoranum oils) against locally isolated Microsporum canis was determined by disc diffusion method and minimum inhibitory concentration was determined using broth dilution method. Mentha piperta oil showed the highest antifungal activity among tested oils in this study. The total inhibition attached when 0.046% was used with M. piperta, the total inhibition obtained with the 0.133% of C. citratus oil, which is accounted as the second essential oils, also T. vulgaris and O. majoranum oils achieved reductions at 0.133%. The present work has revealed that all oils have been used in low concentrations and produced promising results in comparison to the positive control (Clotrimazole).

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Elkhair, E. (2014) Antidermatophytic Activity of Essential Oils against Locally Isolated Microsporum canis—Gaza Strip. Natural Science, 6, 676-684. doi: 10.4236/ns.2014.69067.

Conflicts of Interest

The authors declare no conflicts of interest.


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